Evidence map›Paper›PMID 38129650›Full record

ArticleScientific reports2023

Reconstitution of C9orf72 GGGGCC repeat-associated non-AUG translation with purified human translation factors.

Hayato Ito, Kodai Machida, Mayuka Hasumi, Morio Ueyama, Yoshitaka Nagai, Hiroaki Imataka, Hideki Taguchi

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Cryptic intronic transcriptional initiation generates efficient endogenous mRNA templates for C9orf72-associated RAN translation.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Hayato ItoSchool of Life Science and Technology, Tokyo Institute of Technology, S2-19, Nagatsuta 4259, Midori-ku, Yokohama, 226-8501, Japan.
Kodai MachidaGraduate School of Engineering, University of Hyogo, Shosha, 2167, Himeji, Hyogo, 671-2280, Japan.
Mayuka HasumiSchool of Life Science and Technology, Tokyo Institute of Technology, S2-19, Nagatsuta 4259, Midori-ku, Yokohama, 226-8501, Japan.
Morio UeyamaDepartment of Neurology, Faculty of Medicine, Kindai University, Ohonohigashi 377-2, Osaka-Sayama, 589-8511, Japan.
Yoshitaka NagaiDepartment of Neurology, Faculty of Medicine, Kindai University, Ohonohigashi 377-2, Osaka-Sayama, 589-8511, Japan.
Hiroaki ImatakaGraduate School of Engineering, University of Hyogo, Shosha, 2167, Himeji, Hyogo, 671-2280, Japan.
Hideki TaguchiSchool of Life Science and Technology, Tokyo Institute of Technology, S2-19, Nagatsuta 4259, Midori-ku, Yokohama, 226-8501, Japan. taguchi@bio.titech.ac.jp.
Tokyo Institute of Technology · JPKindai University · JPUniversity of Hyogo · JP

Funding

Japan Science and Technology Agency JPMJFS2112Ministry of Education, Culture, Sports, Science and Technology JP18H03984Ministry of Education, Culture, Sports, Science and Technology JP20H05925Ministry of Education, Culture, Sports, Science and Technology JP21H04763Ministry of Education, Culture, Sports, Science and Technology JP26116002Mitsubishi Foundation 2019-25Uehara Memorial Foundation 2019
6 · The paper itself

Abstract

Nucleotide repeat expansion of GGGGCC (G

Indexed as

C9orf72 ProteinProtein BiosynthesisAmyotrophic Lateral SclerosisFrameshifting, RibosomalFrontotemporal DementiaHeLa CellsHumansIn Vitro TechniquesPeptide Chain Elongation, TranslationalPeptide Chain Initiation, TranslationalPeptide Elongation FactorsC9orf72 ProteinC9orf72 protein, humanPeptide Elongation Factors

Identifiers

PMID38129650
PMCPMC10739749
OpenAlexW4390057498

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.