ArticleScientific reports2023
Medial meniscus extrusion is invariably observed and consistent with tibial osteophyte width in elderly populations: The Bunkyo Health Study.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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12 citing papers in PubMed, 10 citations in OpenAlex.
- The Role of Ultrasound Versus Radiography in Knee Osteoarthritis: A Bilateral Comparative Study.Life (Basel, Switzerland) · 2026Article
- Meniscal extrusion increases with age: Decade-specific magnetic resonance imaging reference values.Journal of experimental orthopaedics · 2026Article
- Meniscal extrusion: Multiple theories, one clinical challenge.Journal of experimental orthopaedics · 2026Article
- Relationship between medial meniscus extrusion and osteophyte formation in early-stage knee osteoarthritis: an ultrasound-based multicenter cross-sectional study.Journal of medical ultrasonics (2001) · 2026Article
- Frequency and mutual associations of knee osteoarthritis features on ultrasound imaging in recent-onset symptomatic knee osteoarthritis patients: A cross-sectional analysis in a convenience sample of Dutch patients.Osteoarthritis and cartilage open · 2026Article
- Meniscal Extrusion: A Key Modifiable Driver of Meniscal and Cartilage Degeneration.Current reviews in musculoskeletal medicine · 2026Review
- Micro-computed tomographical and histopathological analyses of medial tibial plateaus from patients with subchondral insufficiency fracture or osteoarthritis of the knee.Arthritis research & therapy · 2026Article
- Medial plica is associated with progression of medial meniscus extrusion in middle-aged persons with Kellgren-Lawrence grade 0: data from the osteoarthritis initiative.Journal of orthopaedic surgery and research · 2025Article
- Bone marrow lesion coexisted with subchondral bone attrition and/or subchondral bone cyst is associated with knee pain in knee osteoarthritis regardless of cartilage lesion: the Bunkyo health study.Arthritis research & therapy · 2025Article
- Progression of medial meniscal extrusion following anterior cruciate ligament reconstruction correlates with graft diameter: a retrospective longitudinal study.BMC musculoskeletal disorders · 2025Article
- Article
- The changes in 3D bone morphology mediate the association between meniscal extrusion and radiographic progression of osteoarthritis: data from the Osteoarthritis Initiative.Quantitative imaging in medicine and surgery · 2025Article
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Authors and funding
21 authors at 1 institution in 1 country.
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Abstract
We reported that the full-length width of medial tibial osteophytes comprising cartilage and bone parts correlates with medial meniscus extrusion (MME) in early-stage knee osteoarthritis (OA). However, no data exist on the prevalence of MME and its relationship with osteophytes in the elderly population. 1191 elderly individuals (females 57%; 72.9 years old on average) in the Bunkyo Health Study underwent standing plain radiograph and proton density-weighted MRI on knee joints. MRI-detected OA changes were evaluated according to the Whole-Organ Magnetic Resonance Imaging Score. A new method of assessing the cartilage and bone parts of osteophytes was developed using pseudo-coloring images of proton density-weighted fat-suppressed MRI. Most subjects showed Kellgren-Lawrence grade 1 or 2 radiographic medial knee OA (88.1%), MME (98.7%, 3.90 ± 2.01 mm), and medial tibial osteophytes (99.3%, 3.27 ± 1.50 mm). Regarding OA changes, MME was closely associated with the full-length width of medial tibial osteophytes (β = 1.114; 95% CI 1.069-1.159; p < 0.001) in line with osteophyte width (intraclass correlation coefficient, 0.804; 95% CI 0.783-0.823). Our data revealed that MME and medial tibial osteophytes are observed in the elderly and demonstrate that the degree of MME is consistent with the full-length width of medial tibial osteophytes, suggesting that osteophytes might be implicated in MME.
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