Evidence map›Paper›PMID 38129113›Full record

ArticlePhysiological reports2023

Evaluation of a phosphate kinetics model in hemodialysis therapy-Assessment of the temporal robustness of model predictions.

Sisse H Laursen, Lise Boel, Lisbet Brandi, Jeppe H Christensen, Peter Vestergaard, Ole Kristian Hejlesen

Open access · goldAbstract read
In one paragraph

Article in Physiological reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 74% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Sisse H LaursenThe Danish Diabetes Academy, Odense University Hospital, Odense, Denmark.ORCID 0000-0001-5884-8125
Lise BoelDepartment of Clinical Medicine, Aalborg University, Aalborg, Denmark.
Lisbet BrandiDepartment of Cardiology, Nephrology, and Endocrinology, Nordsjaellands Hospital, Hillerød, Denmark.
Jeppe H ChristensenDepartment of Nephrology, Aalborg University Hospital, Aalborg, Denmark.
Peter VestergaardSteno Diabetes Center North Jutland, Aalborg University Hospital, Aalborg, Denmark.
Ole Kristian HejlesenDepartment of Health Science and Technology, Aalborg University, Aalborg, Denmark.
Aalborg University Hospital · DKAalborg University · DKNordsjællands Hospital · DK

Funding

Novo Nordisk Foundation Center for Basic Metabolic Research (NovoNordisk Foundation Center for Basic Metabolic Research) OL8201
6 · The paper itself

Abstract

In-depth understanding of intra- and postdialytic phosphate kinetics is important to adjust treatment regimens in hemodialysis. We aimed to modify and validate a three-compartment phosphate kinetic model to individual patient data and assess the temporal robustness. Intradialytic phosphate samples were collected from the plasma and dialysate of 12 patients during two treatments (HD1 and HD2). 2-h postdialytic plasma samples were collected in four of the patients. First, the model was fitted to HD1 samples from each patient to estimate the mass transfer coefficients. Second, the best fitted model in each patient case was validated on HD2 samples. The best model fits were determined from the coefficient of determination (R

Indexed as

PhosphatesRenal DialysisHumansKineticsPhosphatescompartment modelingdialysishyperphosphatemiakineticsphosphate

Identifiers

PMID38129113
PMCPMC10737683
OpenAlexW4390079774

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.