Evidence map›Paper›PMID 38128061›Full record

ArticleThe European journal of neuroscience2024

Prefrontal cortex hemodynamic activity during a test of lower extremity functional muscle strength in children with cerebral palsy: A functional near-infrared spectroscopy study.

Joel Licea, Owais A Khan, Tarkeshwar Singh, Christopher M Modlesky

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The European journal of neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Joel LiceaDepartment of Kinesiology, University of Georgia, Athens, GA, USA.
Owais A KhanDepartment of Kinesiology, University of Georgia, Athens, GA, USA.
Tarkeshwar SinghDepartment of Kinesiology, The Pennsylvania State University, State College, PA, USA.
Christopher M ModleskyDepartment of Kinesiology, University of Georgia, Athens, GA, USA.
University of Georgia · USPennsylvania State University · US

Funding

Effect of vibration on muscle properties, physical activity and balance in children with cerebral palsyR01HD090126 · NICHD · UNIVERSITY OF GEORGIA · PI MODLESKY, CHRISTOPHER M · 2017 to 2022
$3.0M
Eunice Kennedy Shriver National Institute of Child Health and Human Development R01HD090126NICHD NIH HHS R01 HD090126University of Georgia Athletic Association
6 · The paper itself

Abstract

Children with cerebral palsy (CP) exhibit impaired motor control and significant muscle weakness due to a brain lesion. However, studies that assess the relationship between brain activity and performance on dynamic functional muscle strength assessments in CP are needed. The aim of this study was to determine the effect of a progressive lateral step-up test on prefrontal cortex (PFC) hemodynamic activity in children with CP. Fourteen ambulatory children with spastic CP (Gross Motor Function Classification System level I; 5-11 y) and 14 age- and sex-matched typically developing control children completed a progressive lateral step-up test at incremental step heights (0, 10, 15 and 20 cm) using their non-dominant lower limb. Hemodynamic activity in the PFC was assessed using non-invasive, portable functional neuroimaging (functional near-infrared spectroscopy). Children with CP completed fewer repetitions at each step height and exhibited lower PFC hemodynamic activity across step heights compared to controls. Lower PFC activation in CP was maintained after statistically controlling for the number of repetitions completed at each step height. PFC hemodynamic activity was not associated with LSUT task performance in children with CP, but a positive relationship was observed in controls at the most challenging 20 cm step height. The results suggest there is an altered PFC recruitment pattern in children with CP during a highly dynamic test of functional strength. Further studies are needed to explore the mechanisms underlying the suppressed PFC activation observed in children with CP compared to typically developing children.

Indexed as

Cerebral PalsyChildHemodynamicsHumansLower ExtremityMuscle StrengthPrefrontal CortexSpectroscopy, Near-Infraredbrain activityfNIRSfunctional neuroimagingmotor controlmuscle strengthneurorehabilitationpediatrics

Identifiers

PMID38128061
PMCPMC12694746
OpenAlexW4390047203

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.