Evidence map›Paper›PMID 38127201›Full record

ReviewMolecular biology reports2023

Diagnostic and therapeutic value of EVs in lungs diseases and inflammation.

Ali Afzal, Muhammad Babar Khawar, Ume Habiba, Hanan Afzal, Syeda Eisha Hamid, Mussarat Rafiq, Muddasir Hassan Abbasi, Nadeem Sheikh, Rimsha Abaidullah, Zoya Asif and 1 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular biology reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Ali Afzal *Molecular Medicine and Cancer Therapeutics Lab, Department of Zoology, Faculty of Sciences, University of Central Punjab, Lahore, Pakistan.
Muhammad Babar Khawar *Institute of Translational Medicine, Medical College, Yangzhou University, Yangzhou, China. babarkhawar@yahoo.com.ORCID http://orcid.org/0000-0002-1812-0591
Ume Habiba *Department of Zoology, University of Education, Lahore, Pakistan.
Hanan Afzal *Molecular Medicine and Cancer Therapeutics Lab, Department of Zoology, Faculty of Sciences, University of Central Punjab, Lahore, Pakistan.
Syeda Eisha Hamid *Molecular Medicine and Cancer Therapeutics Lab, Department of Zoology, Faculty of Sciences, University of Central Punjab, Lahore, Pakistan.
Mussarat RafiqCell & Molecular Biology Lab, Institute of Zoology, University of the Punjab, Lahore, Pakistan.
Muddasir Hassan AbbasiDepartment of Zoology, University of Okara, Okara, Punjab, Pakistan.
Nadeem SheikhCell & Molecular Biology Lab, Institute of Zoology, University of the Punjab, Lahore, Pakistan.
Rimsha AbaidullahApplied Molecular Biology and Biomedicine Lab, Department of Zoology, University of Narowal, Narowal, Pakistan.
Zoya AsifApplied Molecular Biology and Biomedicine Lab, Department of Zoology, University of Narowal, Narowal, Pakistan.
Tahaa SaeedDepartment of Biology, Syed Babar Ali School of Science and Engineering, Lahore University of Management Sciences, Lahore, Pakistan.
University of Central Punjab · PKUniversity of Okara · PKUniversity of the Punjab · PKLahore University of Management Sciences · PKShowa University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extracellular vesicles (EVs) are membrane-derived messengers which have been playing an important role in the inflammation and pathogenesis of lung diseases. EVs contain varieties of DNA, RNA, and membrane receptors through which they work as a delivery system for bioactive molecules as well as intracellular communicators. EV signaling mediates tumor progression and metastasis. EVs are linked with many diseases and perform a diagnostic role in lung injury and inflammation so are used to diagnose the severity of diseases. EVs containing a variety of biomolecules communicate with the recipient cells during pathophysiological mechanisms thereby acquiring the attention of clinicians toward the diagnostic and therapeutic potential of EVs in different lung diseases. In this review, we summarize the role of EVs in inflammation with an emphasis on their potential as a novel candidate in the diagnostics and therapeutics of chronic obstructive pulmonary disease, asthma, and sarcoidosis.

Indexed as

Extracellular VesiclesLung InjuryPulmonary Disease, Chronic ObstructiveHumansInflammationLungBiomarkerExtracellular vesiclesInflammationLung diseaseTherapeutics

Identifiers

PMID38127201
OpenAlexW4390062086

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.