Evidence map›Paper›PMID 38127149›Full record

ArticlePlant cell reports2023

Multi-environment GWAS identifies genomic regions underlying grain nutrient traits in foxtail millet (Setaria italica).

Vandana Jaiswal, Tirthankar Bandyopadhyay, Roshan Kumar Singh, Vijay Gahlaut, Mehanathan Muthamilarasan, Manoj Prasad

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Article in Plant cell reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
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3 · Its place in the literature

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4 citing papers in PubMed.

  1. Article
  2. Identifying genetic loci associated with drought tolerance in foxtail millet (Setaria italica).TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026
    Article
  3. Millets for a sustainable future.Journal of experimental botany · 2025
    Review
  4. Article
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5 · Who and what money

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6 authors.

Vandana JaiswalBiotechnology Division, CSIR-Institute of Himalayan Bioresource Technology, Palampur, India. vandana.jaiswal2009@gmail.com.
Tirthankar BandyopadhyayNational Institute of Plant Genome Research, New Delhi, India.
Roshan Kumar SinghNational Institute of Plant Genome Research, New Delhi, India.
Vijay GahlautBiotechnology Division, CSIR-Institute of Himalayan Bioresource Technology, Palampur, India.
Mehanathan MuthamilarasanDepartment of Plant Sciences, School of Life Sciences, University of Hyderabad, Hyderabad, Telangana, India.
Manoj PrasadNational Institute of Plant Genome Research, New Delhi, India. manoj_prasad@nipgr.ac.in.ORCID http://orcid.org/0000-0003-0691-0163

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

key messageA total of 104 foxtail millet accessions were evaluated for 11 nutrients in three environments and 67 high-confidence marker-trait associations (MTAs) were identified. Six SNPs showed pleiotropic effect and associated with two or more nutrients, whereas 24 candidate genes were identified for 28 MTAs involving seven traits. Millets are known for their better nutritional profiles compared to major cereals. Foxtail millet (Setaria italica) is rich in nutrients essential to circumvent malnutrition and hidden hunger. However, the genetic determinants underlying this trait remain elusive. In this context, we evaluated 104 diverse foxtail millet accessions in three different environments (E1, E2, and E3) for 11 nutrients and genotyped with 30K SNPs. The genome-wide association study showed 67 high-confidence (Bonferroni-corrected) marker-trait associations (MTAs) for the nutrients except for phosphorus. Six pleiotropic SNPs were also identified, which were associated with two or more nutrients. Around 24 candidate genes (CGs) were identified for 28 MTAs involving seven nutrients. A total of 17 associated SNPs were present within the gene region, and five (5) were mapped in the exon of the CGs. Significant SNPs, desirable alleles and CGs identified in the present study will be useful in breeding programmes for trait improvement.

Indexed as

Setaria PlantEdible GrainGenome-Wide Association StudyGenomicsNutrientsPlant BreedingNutrientsCandidate geneDesirable alleleMalnutritionMarker–trait associationPleiotropismSingle-nucleotide polymorphism

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.