Evidence map›Paper›PMID 38127067›Full record

ArticleeLife2023

Commensal bacteria maintain a Qa-1

Jian Guan, J David Peske, Michael Manoharan Valerio, Chansu Park, Ellen A Robey, Scheherazade Sadegh-Nasseri

Open access · goldAbstract read
In one paragraph

Article in eLife, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Coincident epithelial signals restrain commensal-specific CD8αβbioRxiv : the preprint server for biology · 2026
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Jian GuanDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, United States.ORCID 0000-0002-0118-6578
J David PeskeDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, United States.
Michael Manoharan ValerioDivision of Immunology and Molecular Medicine, Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States.
Chansu ParkDepartment of Pathology, Johns Hopkins University School of Medicine, Baltimore, United States.
Ellen A Robey *Division of Immunology and Molecular Medicine, Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States.ORCID 0000-0002-3630-5266
Scheherazade Sadegh-Nasseri *Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, United States.ORCID 0000-0002-8127-1720
Johns Hopkins University · USUniversity of California, Berkeley · US

Funding

Training Research Educators in Minnesota (TREM) whilst increasing diversityK12GM119955 · NIGMS · UNIVERSITY OF MINNESOTA · PI David Irwin Greenstein, Julia Willett · 2017 to 2026
$6.5M
Immunology & Pathogenesis Program Training GrantT32AI100829 · NIAID · UNIVERSITY OF CALIFORNIA BERKELEY · PI Gregory M Barton, ELLEN A ROBEY · 2012 to 2026
$4.7M
Antigen Processing in the Secretory PathwayR37AI060040 · NIAID · UNIVERSITY OF CALIFORNIA BERKELEY · PI SADEGH-NASSERI, SCHEHERAZADE · 2012 to 2021
$4.2M
Genetic regulation and immunological function of ERAP2 haplotypesR01AI136972 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI YE, CHUN JIMMIE · 2018 to 2022
$3.5M
Presentation of Qa-1 restricted peptides during homeostasis and viral infectionR01AI149341 · NIAID · UNIVERSITY OF CALIFORNIA BERKELEY · PI COSCOY, LAURENT, ROBEY, ELLEN A · 2020 to 2024
$2.9M
Immune Surveillance of Antigen Processing PathwayR01AI130210 · NIAID · UNIVERSITY OF CALIFORNIA BERKELEY · PI SADEGH-NASSERI, SCHEHERAZADE · 2017 to 2021
$2.8M
Opportunities for Pathology Trainees in Cancer ResearchT32CA193145 · NCI · JOHNS HOPKINS UNIVERSITY · PI ANDERS, ROBERT A., EBERHART, CHARLES G · 2015 to 2025
$2.6M
NCI NIH HHS T32 CA193145NIAID NIH HHS R01 AI130210NIAID NIH HHS R01 AI136972NIAID NIH HHS R01 AI149341NIAID NIH HHS R37 AI060040NIAID NIH HHS T32 AI100829NIGMS NIH HHS K12 GM119955NIH HHS R01AI130210NIH HHS R01AI149341NIH HHS R37AI060040
6 · The paper itself

Abstract

Intestinal intraepithelial lymphocytes (IELs) are characterized by an unusual phenotype and developmental pathway, yet their specific ligands and functions remain largely unknown. Here by analysis of QFL T cells, a population of CD8

Indexed as

BacteriaCD8-Positive T-LymphocytesAnimalsCytokinesEpitheliumIntestinal MucosaMiceCytokinesIELimmunologyinflammationMHC-Emicrobiotamouseunconventional T

Identifiers

PMID38127067
PMCPMC10735220
OpenAlexW4386255677

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.