Evidence map›Paper›PMID 38126797›Full record

ArticleRNA biology2024

CCAR-1 works together with the U2AF large subunit UAF-1 to regulate alternative splicing.

Doreen I Lugano, Lindsey N Barrett, Dale Chaput, Margaret A Park, Sandy D Westerheide

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RNA biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Doreen I Lugano
Lindsey N Barrett
Dale Chaput
Margaret A Park
Sandy D WesterheideDepartment of Cell Biology, Microbiology, and Molecular Biology, University of South Florida, Tampa, FL, USA.
Schlumberger (Ireland) · IEUniversity of South Florida · US

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
Regulation of the C. elegans heat shock response by LST-3R15AG052149 · NIA · UNIVERSITY OF SOUTH FLORIDA · PI WESTERHEIDE, SANDRA D. · 2016 to 2016
$440k
NIA NIH HHS R15 AG052149NIH HHS P40 OD010440
6 · The paper itself

Abstract

The Cell Division Cycle and Apoptosis Regulator (CCAR) protein family members have recently emerged as regulators of alternative splicing and transcription, as well as having other key physiological functions. For example, mammalian CCAR2/DBC1 forms a complex with the zinc factor protein ZNF326 to integrate alternative splicing with RNA polymerase II transcriptional elongation in AT-rich regions of the DNA. Additionally,

Indexed as

Alternative SplicingCaenorhabditis elegansCaenorhabditis elegans ProteinsMembrane ProteinsRibonucleoproteinsAnimalsBase SequenceRNA SplicingSplicing Factor U2AFCaenorhabditis elegans Proteinsccar-1 protein, C elegansMembrane ProteinsRibonucleoproteinsSplicing Factor U2AFUAF-1 protein, C elegansalternative splicingCCAR-1C. elegansRNA sequencingUAF-1

Identifiers

PMID38126797
PMCPMC10761121
OpenAlexW4390049951

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.