Evidence map›Paper›PMID 38126751›Full record

ArticlemBio2024

Homologous acetone carboxylases select Fe(II) or Mn(II) as the catalytic cofactor.

Krista A Shisler, William M Kincannon, Jenna R Mattice, James Larson, Adam Valaydon-Pillay, Florence Mus, Tamara Flusche, Arnab Kumar Nath, Sebastian A Stoian, Simone Raugei and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mBio, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 67% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Krista A ShislerInstitute of Biological Chemistry, Washington State University, Pullman, Washington, USA.
William M KincannonDepartment of Chemistry and Biochemistry, Montana State University, Bozeman, Montana, USA.
Jenna R MatticeDepartment of Chemistry and Biochemistry, Montana State University, Bozeman, Montana, USA.
James LarsonDepartment of Chemistry and Biochemistry, Montana State University, Bozeman, Montana, USA.
Adam Valaydon-PillayDepartment of Chemistry, University of Idaho, Moscow, Idaho, USA.
Florence MusInstitute of Biological Chemistry, Washington State University, Pullman, Washington, USA.
Tamara FluscheDepartment of Chemistry and Biochemistry, University of Oklahoma, Norman, Oklahoma, USA.
Arnab Kumar NathDepartment of Chemistry and Biochemistry, Montana State University, Bozeman, Montana, USA.
Sebastian A StoianDepartment of Chemistry, University of Idaho, Moscow, Idaho, USA.
Simone RaugeiPhysical Sciences Division, Pacific Northwest National Laboratory, Richland, Washington, USA.
Brian BothnerDepartment of Chemistry and Biochemistry, Montana State University, Bozeman, Montana, USA.ORCID 0000-0003-1295-9609
Jennifer L DuBoisDepartment of Chemistry and Biochemistry, Montana State University, Bozeman, Montana, USA.ORCID 0000-0001-5593-3391
John W PetersInstitute of Biological Chemistry, Washington State University, Pullman, Washington, USA.ORCID 0000-0001-9117-9568
Montana State University · USPacific Northwest National Laboratory · USUniversity of Idaho · USWashington State University · USUniversity of Oklahoma · US

Funding

Research Core (Developmental Research Project Program)P20GM103474 · NIGMS · MONTANA STATE UNIVERSITY - BOZEMAN · PI Jeffrey Good · 2012 to 2026
$60.0M
Understanding how heme and iron are metabolized by anaerobic commensal bacteria and host-microbiome communitiesR35GM136390 · NIGMS · MONTANA STATE UNIVERSITY - BOZEMAN · PI Jennifer L DuBois · 2020 to 2026
$2.2M
Ultra Performance Liquid Chromatography Tandem Mass Spectrometer for MetabolomicsS10OD028650 · OD · MONTANA STATE UNIVERSITY - BOZEMAN · PI BOTHNER, BRIAN P · 2020 to 2020
$599k
NIGMS NIH HHS P20 GM103474NIGMS NIH HHS R35 GM136390NIH HHS S10 OD028650
6 · The paper itself

Abstract

Acetone carboxylases (ACs) catalyze the metal- and ATP-dependent conversion of acetone and bicarbonate to form acetoacetate. Interestingly, two homologous ACs that have been biochemically characterized have been reported to have different metal complements, implicating different metal dependencies in catalysis. ACs from proteobacteria

Indexed as

AcetoneCoordination ComplexesAcetoacetatesBicarbonatesCatalysisFerrous CompoundsManganeseMetalsAcetoacetatesacetoacetic acidAcetoneBicarbonatesCoordination ComplexesFerrous CompoundsManganeseMetalsacetonecarboxylaseCO2 fixationironmanganese

Identifiers

PMID38126751
PMCPMC10865871
OpenAlexW4390060873

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.