ArticlemBio2024
Gallic acid ameliorates colitis by trapping deleterious metabolite ammonia and improving gut microbiota dysbiosis.
Article in mBio, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 33 citations in OpenAlex.
- Targeted intestinal barrier repairActa pharmaceutica Sinica. B · 2026Article
- Article
- Update on the role of mycobiome in Gastrointestinal cancers: mechanisms and therapeutic implications.Medical oncology (Northwood, London, England) · 2025Review
- Glucose may be biotransformed and then react with alcohol, fats, endocannabinoids, or various amino acids to form dopamine or norepinephrineFrontiers in pharmacology · 2025Article
- Miniature rose alleviates inflammatory bowel disease in mice by modulating gut microbiota, inhibiting TLR4, enhancing tight junction proteins, and promoting metabolism.Frontiers in microbiology · 2025Article
- The role of plant-based dietary compounds in gut microbiota modulation in inflammatory bowel disease.Frontiers in nutrition · 2025Review
- Compound Sophorae Decoction Alleviates Ferroptosis in Colitis Rats via Activating Keap1/Nrf2/GPX4 Signaling Pathway.Gastroenterology research and practice · 2025Article
- Gallic acid prevents obesity in mice on a high-fat diet via the gut microbiota-adipose tissue axis.Current research in food science · 2025Article
- Therapeutic Implications of Phenolic Acids for Ameliorating Inflammatory Bowel Disease.Nutrients · 2024Review
- Navigating the signaling landscape of Ralstonia solanacearum: a study of bacterial two-component systems.World journal of microbiology & biotechnology · 2024Review
- Harnessing the Anti-Inflammatory Properties of Polyphenols in the Treatment of Inflammatory Bowel Disease.International journal of biological sciences · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 3 institutions in 2 countries.
Funding
Abstract
Gut microbiota dysbiosis is causally related to inflammatory bowel disease (IBD), and increased levels of the gut metabolite ammonia have been proposed to contribute to IBD development. In this study, we aimed to clarify the anti-colitis mechanism of gallic acid (GA) based on its ability to trap the deleterious metabolite ammonia and improve gut microbiota. Aminated product was detected in the fecal samples of mice after oral gavage of gallic acid (GA) and identified as 4-amino-substituted gallic acid (4-NH
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.