Evidence map›Paper›PMID 38126513›Full record

ArticleArquivos brasileiros de cardiologia2023

Exaggerated Systolic Blood Pressure Increase with Exercise and Myocardial Ischemia on Exercise Stress Echocardiography.

Cláudia Bispo Martins-Santos, Lara Teles Alencar Duarte, Cleovaldo Ribeiro Ferreira-Junior, Allexa Gabriele Teixeira Feitosa, Edvaldo Victor Gois Oliveira, Iana Carine Machado Bispo Campos, Enaldo Vieira de Melo, Stephanie Macedo Andrade, Antônio Carlos Sobral Sousa, Joselina Luzia Menezes Oliveira

Open access · diamondAbstract read
In one paragraph

Article in Arquivos brasileiros de cardiologia, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Guideline on Stress Echocardiography - 2026.Arquivos brasileiros de cardiologia · 2026
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Cláudia Bispo Martins-SantosUniversidade Federal de Sergipe , São Cristóvão , SE - Brasil.ORCID 0000-0002-3749-5284
Lara Teles Alencar DuarteUniversidade Federal de Sergipe , São Cristóvão , SE - Brasil.
Cleovaldo Ribeiro Ferreira-JuniorUniversidade Federal de Sergipe , São Cristóvão , SE - Brasil.
Allexa Gabriele Teixeira FeitosaUniversidade Federal de Sergipe , São Cristóvão , SE - Brasil.
Edvaldo Victor Gois OliveiraUniversidade Federal de Sergipe , São Cristóvão , SE - Brasil.
Iana Carine Machado Bispo CamposRede D'Or São Luiz - Clínica e Hospital São Lucas , Aracaju , SE - Brasil.
Enaldo Vieira de MeloUniversidade Federal de Sergipe , São Cristóvão , SE - Brasil.
Stephanie Macedo AndradeRede D'Or São Luiz - Clínica e Hospital São Lucas , Aracaju , SE - Brasil.
Antônio Carlos Sobral SousaUniversidade Federal de Sergipe , São Cristóvão , SE - Brasil.ORCID 0000-0002-4158-9726
Joselina Luzia Menezes OliveiraUniversidade Federal de Sergipe , São Cristóvão , SE - Brasil.ORCID 0000-0002-4325-0590
Universidade Federal de Sergipe · BRBeneficência Portuguesa de São Paulo · BRHospital São Lucas da PUCRS · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCentral Illustration : Exaggerated Systolic Blood Pressure Increase with Exercise and Myocardial Ischemia on Exercise Stress Echocardiography ESBPRE: exaggerated systolic blood pressure response to exercise; HR: heart rate; SBP: systolic blood pressure.

backgroundThe association between exaggerated systolic blood pressure response to exercise (ESBPRE) and myocardial ischemia is controversial and little studied in patients with established or suspected chronic coronary syndrome.

objectiveTo verify the relationship between myocardial ischemia and ESBPRE in patients undergoing exercise stress echocardiography (ESE).

methodsThis is a cross-sectional study with 14,367 patients undergoing ESE, from January 2000 to January 2022, divided into the following 2 groups: G1, composed of patients whose peak systolic pressure increased ≥ 90 mmHg (value corresponding to the 95th percentile of the study population), and G2, patients who did not demonstrate an exaggerated hypertensive response. The groups were compared using Student's t and chi-square tests. P values < 0.05 were considered significant. Logistic regression was also performed to identify independent risk factors for myocardial ischemia, ESBPRE, complaints of typical chest pain prior to the exam, and angina during the test.

resultsOf the 14,367 patients, 1,500 (10.4%) developed ESBPRE, and 7,471 (52.0%) were female. The percentages of previous complaints of typical chest pain, angina during the test, and myocardial ischemia in patients with ESBPRE were 5.8%, 2.4% and 18.1%, compared to 7.4%, 3.9%, and 24.2%, in patients without ESBPRE, respectively (p = 0.021,p = 0.004, p < 0.001). In multivariate analysis, ESBPRE was independently associated with a lower probability of myocardial ischemia (odds ratio: 0.73; 95% confidence interval: 0.58 to 0.93; p = 0.009).

conclusionExaggerated increase in systolic blood pressure during ESE may be a marker for excluding myocardial ischemia.

Indexed as

Coronary Artery DiseaseMyocardial IschemiaAngina PectorisBlood PressureCross-Sectional StudiesEchocardiography, StressExercise TestFemaleHumansMale

Identifiers

PMID38126513
PMCPMC10773463
OpenAlexW4389491730

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.