Evidence map›Paper›PMID 38126086›Full record

ArticleJournal of applied physiology (Bethesda, Md. : 1985)2024

Acute fasting reduces tolerance to progressive central hypovolemia in humans.

Joshua E Gonzalez, William H Cooke

Open access · greenAbstract read
In one paragraph

Article in Journal of applied physiology (Bethesda, Md. : 1985), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Joshua E GonzalezOregon Institute of Occupational Health Sciences, Oregon Health & Science University, Portland, Oregon, United States.ORCID 0000-0003-0680-7852
William H CookeDepartment of Kinesiology & Integrative Physiology, Michigan Technological University, Houghton, Michigan, United States.
Michigan Technological University · US

Funding

Multidisciplinary Research Training in Pulmonary MedicineT32HL083808 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI LEWINSOHN, DAVID M., SLATORE, CHRISTOPHER G. · 2008 to 2025
$5.3M
HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) T32HL083808Michigan Space Grant Consortium (MSGC)NHLBI NIH HHS T32 HL083808Oregon Health and Science University Fellowship for Diversity in ResearchPortage Health Foundation (PHF)
6 · The paper itself

Abstract

Potential health benefits of an acute fast include reductions in blood pressure and increases in vagal cardiac control. These purported health benefits could put fasted humans at risk for cardiovascular collapse when exposed to central hypovolemia. The purpose of this study was to test the hypothesis that an acute 24-h fast (vs. 3-h postprandial) would reduce tolerance to central hypovolemia induced via lower body negative pressure (LBNP). We measured blood ketones (β-OHB) to confirm a successful fast (

Indexed as

HemodynamicsHypovolemiaBlood PressureBlood VolumeFastingHeart RateHumansKetonesLower Body Negative PressureKetonesfastingfood deprivationhemorrhagelower body negative pressure

Identifiers

PMID38126086
PMCPMC11219002
OpenAlexW4390053552

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.