Evidence map›Paper›PMID 38126036›Full record

ArticleOncoimmunology2023

g-NK cells from umbilical cord blood are phenotypically and functionally different than g-NK cells from peripheral blood.

Fei Gao, Mauricio Campos Mora, Michael Constantinides, Loïs Coenon, Caroline Multrier, Loïc Vaillant, Tianxiang Zhang, Martin Villalba

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oncoimmunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Fei GaoDepartment of Pathology, School of Basic Medicine, Central South University, Changsha, China.ORCID 0000-0003-4856-0261
Mauricio Campos MoraIRMB, INSERM, CHRU de Montpellier, University Montpellier, Montpellier, France.
Michael ConstantinidesIRMB, INSERM, CHRU de Montpellier, University Montpellier, Montpellier, France.
Loïs CoenonIRMB, INSERM, CHRU de Montpellier, University Montpellier, Montpellier, France.
Caroline MultrierIRMB, INSERM, CHRU de Montpellier, University Montpellier, Montpellier, France.
Loïc VaillantIRMB, INSERM, CHRU de Montpellier, University Montpellier, Montpellier, France.
Tianxiang ZhangDepartment of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.
Martin VillalbaIRMB, INSERM, CHRU de Montpellier, University Montpellier, Montpellier, France.
Inserm · FRCentral South University · CNCentre National de la Recherche Scientifique · FRYale University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

FcRγ-deficient natural killer (NK) cells, designated as g-NK cells, exhibit enhanced antibody-dependent cellular cytotoxicity (ADCC) capacity and increased IFN-γ and TNF-α production, rendering them promising for antiviral and antitumor responses. g-NK cells from peripheral blood (PB) are often associated with prior human cytomegalovirus (HCMV) infection. However, the prevalence, phenotype, and function of g-NK cells in umbilical cord blood (UCB-g-NK) remain unclear. Here, we demonstrate significant phenotypical differences between UCB-g-NK and PB-g-NK cells. Unlike PB-g-NK cells, UCB-g-NK cells did not show heightened cytokine production upon CD16 engagement, in contrast to the conventional NK (c-NK) cell counterparts. Interestingly, following

Indexed as

Fetal BloodLymphocyte ActivationAdultAntibody-Dependent Cell CytotoxicityCytomegalovirusHumansKiller Cells, NaturalADCCg-NK+ plasmaPB-g-NKUCB-g-NK

Identifiers

PMID38126036
PMCPMC10732642
OpenAlexW4388902658

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.