Evidence map›Paper›PMID 38126023›Full record

ArticleAutophagy reports2022

The link between inhibition of PI3K signaling, induction of autophagy, and elimination of organelles to form the lens organelle-free zone.

A Sue Menko

Open access · diamondAbstract read
In one paragraph

Article in Autophagy reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Autophagy in ocular diseases: from mechanisms to therapeutic potential.Frontiers in cell and developmental biology · 2026
    Review
  3. The link of FOXO1 and FOXO4 transcription factors to development of the lens.Developmental dynamics : an official publication of the American Association of Anatomists · 2025
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

A Sue MenkoDepartment of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, PA.
Thomas Jefferson University · US

Funding

Repurposing classical death pathways for signaling roles in lens differentiationR01EY026478 · NEI · THOMAS JEFFERSON UNIVERSITY · PI A. Sue Menko · 2016 to 2026
$5.8M
NEI NIH HHS R01 EY026478
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AKTautophagydevelopmentdifferentiationlensnucleiorganelle free zone (OFZ)organellesPI3Ksignaling

Identifiers

PMID38126023
PMCPMC10732338
OpenAlexW4281614584

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.