Evidence map›Paper›PMID 38125909›Full record

ArticleFrontiers in cellular and infection microbiology2023

Understanding the diagnosis of catheter-related bloodstream infection: real-time monitoring of biofilm growth dynamics using time-lapse optical microscopy.

Marta Díaz-Navarro, Rafael Samaniego, Juan Carlos Piqueras, Rafael Díez, Rama Hafian, Irene Manzano, Patricia Muñoz, María Guembe

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. mBio · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Marta Díaz-NavarroDepartment of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
Rafael SamaniegoInstituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain.
Juan Carlos PiquerasSchool of Biology, Universidad Complutense de Madrid, Madrid, Spain.
Rafael DíezSchool of Biology, Universidad Complutense de Madrid, Madrid, Spain.
Rama HafianSchool of Biology, Universidad Complutense de Madrid, Madrid, Spain.
Irene ManzanoSchool of Biology, Universidad Complutense de Madrid, Madrid, Spain.
Patricia MuñozDepartment of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
María GuembeDepartment of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
Universidad Complutense de Madrid · ESHospital General Universitario Gregorio Marañón · ESCentro de Investigación Biomédica en Red de Enfermedades Respiratorias · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The differential time to positivity (DTTP) technique is recommended for the conservative diagnosis of catheter-related bloodstream infection (C-RBSI). The technique is based on a 120-minute difference between microbial growth in blood drawn through the catheter and blood drawn through a peripheral vein. However, this cut-off has failed to confirm C-RBSI caused by Objective: We hypothesized that the biofilm of both microorganisms disperses faster than that of other microorganisms and that microbial load is rapidly equalized between catheter and peripheral blood. Therefore, our aim was to compare the biofilm dynamics of various microorganisms. Methods: Biofilm of ATCC strains of methicillin-resistant Results: The mean (standard deviation) dispersal time in Conclusion: Our findings could explain why early dissemination of cells in

Indexed as

Catheter-Related InfectionsMethicillin-Resistant Staphylococcus aureusSepsisBiofilmsCandida albicansCathetersEscherichia coliHumansMicroscopyStaphylococcus aureusStaphylococcus epidermidisTime-Lapse Imagingbiofilmcatheter-related bloodstream infectionsdifferential time to positivitygrowthtime-lapse optical microscopy

Identifiers

PMID38125909
PMCPMC10731284
OpenAlexW4389393049

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.