Evidence map›Paper›PMID 38125463›Full record

ArticleHeliyon2023

Genetic diversity of

Mulualem Agonafir, Gurja Belay, Nontuthuko E Maningi, Adey Feleke, Melese Abate Reta, Sharon L Olifant, Mohammed Suaudi Hassen, Tewodros Girma, P Bernard Fourie

Open access · goldAbstract read
In one paragraph

Article in Heliyon, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Genetic diversity ofNew microbes and new infections · 2024
    Article
  7. Genetic Diversity ofPathogens (Basel, Switzerland) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Mulualem AgonafirDepartment of Microbial, Cellular and Molecular Biology, College of Natural Sciences, Addis Ababa University, Ethiopia.
Gurja BelayDepartment of Microbial, Cellular and Molecular Biology, College of Natural Sciences, Addis Ababa University, Ethiopia.
Nontuthuko E ManingiDepartment of Medical Microbiology, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa.
Adey FelekeDepartment of Microbial, Cellular and Molecular Biology, College of Natural Sciences, Addis Ababa University, Ethiopia.
Melese Abate RetaDepartment of Medical Microbiology, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa.
Sharon L OlifantDepartment of Medical Microbiology, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa.
Mohammed Suaudi HassenAdama Public Health Research and Referral Laboratory Center, Adama, Ethiopia.
Tewodros GirmaHarar Health Research and Regional Laboratory, Harar, Ethiopia.
P Bernard FourieDepartment of Medical Microbiology, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa.
Addis Ababa University · ETUniversity of Pretoria · ZAAdama Science and Technology University · ETWoldia University · ET

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The population structure of Methods: A total of 223 MTBC culture isolates obtained from patients referred to Adama and Harar TB reference laboratories were spoligotyped. Demographic and clinical characteristics were collected. Results: Six major lineages: Euro-American (Lineage 4), East-African-Indian (Lineage 3), East Asian (Lineage 2), Indo-Oceanic (Lineage 1), Conclusion: We found a heterogeneous population structure of MTBC dominated by T and CAS families, and the Euro-American lineage. The identification of the Beijing strain, particularly the rare SIT541 spoligotype in Eastern Ethiopia, warrants a heightened surveillance plan, as little is known about this genotype. A large-scale investigation utilizing a tool with superior discriminatory power, such as whole genome sequencing, is necessary to gain a thorough understanding of the genetic diversity of MTBC in the nation, which would help direct the overall control efforts.

Indexed as

EthiopiaGenetic diversityLineageMycobacterium tuberculosis complexSpoligotypingSub-lineage

Identifiers

PMID38125463
PMCPMC10731068
OpenAlexW4389151806

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.