Evidence map›Paper›PMID 38124780›Full record

ArticleCase reports in hematology2023

Gilteritinib Monotherapy as a Transplant Bridging Option for a Patient with

Hirofumi Kobayashi, Hiroki Tsutsumi, Yukiko Misaki, Takashi Maekawa, Naoko Inoshita, Machiko Kawamura, Nobuo Maseki

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in hematology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. [The cure for acute promyelocytic leukemia and China's contributions].Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Hirofumi KobayashiDepartment of Hematology, Saitama Cancer Center, Saitama, Japan.ORCID https://orcid.org/0009-0000-3588-3788
Hiroki TsutsumiDepartment of Hematology, Saitama Cancer Center, Saitama, Japan.
Yukiko MisakiDivision of Hematology, Jichi Medical University Saitama Medical Center, Saitama, Japan.
Takashi MaekawaDepartment of Pathology, Saitama Cancer Center, Saitama, Japan.
Naoko InoshitaDepartment of Pathology, Saitama Cancer Center, Saitama, Japan.
Machiko KawamuraDepartment of Hematology, Saitama Cancer Center, Saitama, Japan.ORCID https://orcid.org/0000-0002-6138-1690
Nobuo MasekiDepartment of Hematology, Saitama Cancer Center, Saitama, Japan.ORCID https://orcid.org/0000-0002-3088-6311
Saitama Cancer Center · JPJichi Medical University · JPMaruyama Memorial General Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a case of FLT3-mutated APL who developed disease relapse despite all-trans retinoic acid (ATRA) + chemotherapy, and re-induction chemotherapy with arsenic trioxide (ATO) and high-dose (HD) cytarabine (Ara-C) therapy failed to yield complete remission. Because the leukemic cells were resistant to all the aforementioned therapies, we started the patient on monotherapy with gilteritinib, a selective FLT3-inhibitor, as an alternative re-induction treatment option rather than further intensive chemotherapy. The patient showed complete hematologic remission in response to this therapy. This case serves as supporting evidence for the use of single-agent therapy with gilteritinib as a bridge to transplantation in patients with refractory

Identifiers

PMID38124780
PMCPMC10732830
OpenAlexW4389664960

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.