Evidence map›Paper›PMID 38124314›Full record

ArticleGlobal spine journal2025

Analysis of Personalized Interbody Implants in the Surgical Treatment of Adult Spinal Deformity.

Justin S Smith, Gregory M Mundis, Joseph A Osorio, Rodrigo J Nicolau, Michele Temple-Wong, Renaud Lafage, Shay Bess, Christopher P Ames

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Global spine journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

Justin S SmithDepartment of Neurosurgery, University of Virginia, Charlottesville, VA, USA.ORCID 0000-0003-0467-5534
Gregory M MundisDepartment of Orthopedic Surgery, Scripps Clinic, San Diego, CA, USA.
Joseph A OsorioDepartment of Neurological Surgery, University of California, San Diego, San Diego, CA, USA.
Rodrigo J NicolauCarlsmed, Carlsbad, CA, USA.
Michele Temple-WongCarlsmed, Carlsbad, CA, USA.
Renaud LafageDepartment of Orthopedic Surgery, Lennox Hill Hospital, New York City, NY, USA.ORCID 0000-0002-4820-1835
Shay BessPresbyterian St Lukes Medical Center, Denver, CO, USA.
Christopher P AmesDepartment of Neurological Surgery, University of California, San Francisco, San Francisco, CA, USA.
Lenox Hill Hospital · USPresbyterian St. Luke's Medical Center · USScripps Clinic · USUniversity of California, San Francisco · USUniversity of California System · USUniversity of Virginia · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designMulticenter cohort.

objectivesA report from the International Spine Study Group (ISSG) noted that surgeons failed to achieve alignment goals in nearly two-thirds of 266 complex adult deformity surgery (CADS) cases. We assess whether personalized interbody spacers are associated with improved rates of achieving goal alignment following adult spinal deformity (ASD) surgery.

methodsASD patients were included if their surgery utilized 3D-printed personalized interbody spacer(s) and they met ISSG CADS inclusion criteria. Planned alignment was personalized by the surgeon during interbody planning. Planned vs achieved alignment was assessed and compared with the ISSG CADS series that used stock interbodies.

resultsFor 65 patients with personalized interbodies, 62% were women, mean age was 70.3 years (SD = 8.3), mean instrumented levels was 9.9 (SD = 4.1), and the mean number of personalized interbodies per patient was 2.2 (SD = .8). Segmental alignment was achieved close to plan for levels with personalized interbodies, with mean difference between goal and achieved as follows: intervertebral lordosis = .9° (SD = 5.2°), intervertebral coronal angle = .1° (SD = 4.7°), and posterior disc height = -0.1 mm (SD = 2.3 mm). Achieved pelvic incidence-to-lumbar lordosis mismatch (PI-LL) correlated significantly with goal PI-LL (r = .668,

conclusionsThis study supports use of personalized interbodies as a means of better achieving goal segmental sagittal and coronal alignment and significantly improving achievement of goal PI-LL compared with stock devices.

Indexed as

adult spinal deformityalignmentinterbody fusionpersonalized implantssurgerythoracolumbar spinal deformity

Identifiers

PMID38124314
PMCPMC11877536
OpenAlexW4388846537

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.