Evidence map›Paper›PMID 38124211›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2024

Intermittent Hypobaric Hypoxia Ameliorates Autistic-Like Phenotypes in Mice.

Yi-da Pan, Yuan Zhang, Wen-Ying Zheng, Min-Zhen Zhu, Huan-Yu Li, Wen-Jie Ouyang, Qin-Qing Wen, Xin-Hong Zhu

Open access · greenAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Hemoglobin as an oxygen gasoreceptor.Acta biochimica Polonica · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Yi-da PanSchool of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.
Yuan ZhangSchool of Psychology, Shenzhen University, Shenzhen 518060, China.
Wen-Ying ZhengResearch Center for Brain Health, Pazhou Lab, Guangzhou 510330, China.
Min-Zhen ZhuResearch Center for Brain Health, Pazhou Lab, Guangzhou 510330, China.
Huan-Yu LiResearch Center for Brain Health, Pazhou Lab, Guangzhou 510330, China.
Wen-Jie OuyangResearch Center for Brain Health, Pazhou Lab, Guangzhou 510330, China.
Qin-Qing WenResearch Center for Brain Health, Pazhou Lab, Guangzhou 510330, China.
Xin-Hong ZhuSchool of Basic Medical Sciences, Southern Medical University, Guangzhou 510515, China.
Shenzhen University · CNGuangdong 999 Brain Hospital · CNSouth China University of Technology · CNSouthern Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by persistent deficits in social communication and stereotyped behaviors. Although major advances in basic research on autism have been achieved in the past decade, and behavioral interventions can mitigate the difficulties that individuals with autism experience, little is known about the many fundamental issues of the interventions, and no specific medication has demonstrated efficiency for the core symptoms of ASD. Intermittent hypobaric hypoxia (IHH) is characterized by repeated exposure to lowered atmospheric pressure and oxygen levels, which triggers multiple physiological adaptations in the body. Here, using two mouse models of ASD, male

Indexed as

Autism Spectrum DisorderAutistic DisorderAnimalsDorsal Raphe NucleusFragile X Messenger Ribonucleoprotein 1HypoxiaMaleMicePhenotypeSerotonergic NeuronsFmr1 protein, mouseFragile X Messenger Ribonucleoprotein 1autism spectrum disorderdorsal raphe nucleus (DRN)hypoxia inducible factor (HIF) 1αintermittent hypobaric hypoxia (IHH)serotonergic neurons

Identifiers

PMID38124211
PMCPMC10869151
OpenAlexW4389981757

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.