Evidence map›Paper›PMID 38124111›Full record

ArticleCancer imaging : the official publication of the International Cancer Imaging Society2023

Breast cancer detection accuracy of AI in an entire screening population: a retrospective, multicentre study.

Mohammad Talal Elhakim, Sarah Wordenskjold Stougaard, Ole Graumann, Mads Nielsen, Kristina Lång, Oke Gerke, Lisbet Brønsro Larsen, Benjamin Schnack Brandt Rasmussen

Abstract readMulticenter Study
In one paragraph

Article in Cancer imaging : the official publication of the International Cancer Imaging Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Artificial intelligence in mammography: a systematic review of the external validation.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2024
    Pooled it
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mohammad Talal ElhakimDepartment of Radiology, Odense University Hospital, Kløvervaenget 47, Entrance 27, Ground floor, 5000, Odense C, Denmark. mte@rsyd.dk.ORCID http://orcid.org/0000-0002-2673-2352
Sarah Wordenskjold StougaardDepartment of Clinical Research, University of Southern Denmark, Kløvervaenget 10, Entrance 112, 2nd floor, 5000, Odense C, Denmark.
Ole GraumannDepartment of Clinical Research, University of Southern Denmark, Kløvervaenget 10, Entrance 112, 2nd floor, 5000, Odense C, Denmark.
Mads NielsenDepartment of Computer Science, University of Copenhagen, Universitetsparken 1, 2100, København Ø, Denmark.
Kristina LångDepartment of Translational Medicine, Lund University, Inga Maria Nilssons gata 47, SE-20502, Malmö, Sweden.
Oke GerkeDepartment of Clinical Research, University of Southern Denmark, Kløvervaenget 10, Entrance 112, 2nd floor, 5000, Odense C, Denmark.
Lisbet Brønsro LarsenDepartment of Radiology, Odense University Hospital, Kløvervaenget 47, Entrance 27, Ground floor, 5000, Odense C, Denmark.
Benjamin Schnack Brandt RasmussenDepartment of Radiology, Odense University Hospital, Kløvervaenget 47, Entrance 27, Ground floor, 5000, Odense C, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundArtificial intelligence (AI) systems are proposed as a replacement of the first reader in double reading within mammography screening. We aimed to assess cancer detection accuracy of an AI system in a Danish screening population.

methodsWe retrieved a consecutive screening cohort from the Region of Southern Denmark including all participating women between Aug 4, 2014, and August 15, 2018. Screening mammograms were processed by a commercial AI system and detection accuracy was evaluated in two scenarios, Standalone AI and AI-integrated screening replacing first reader, with first reader and double reading with arbitration (combined reading) as comparators, respectively. Two AI-score cut-off points were applied by matching at mean first reader sensitivity (AI

resultsOut of 272,008 screening mammograms from 158,732 women, 257,671 (94.7%) with adequate image data were included in the final analyses. Sensitivity and specificity were 63.7% (95% CI 61.6%-65.8%) and 97.8% (97.7-97.8%) for first reader, and 73.9% (72.0-75.8%) and 97.9% (97.9-98.0%) for combined reading, respectively. Standalone AI

conclusionsReplacing first reader in double reading with an AI could be feasible but choosing an appropriate AI threshold is crucial to maintaining cancer detection accuracy and workload.

Indexed as

Breast NeoplasmsArtificial IntelligenceEarly Detection of CancerFemaleHumansMammographyMass ScreeningRetrospective StudiesArtificial intelligenceBreast cancerDeep learningDouble readingMammography screening

Identifiers

PMID38124111
PMCPMC10731688

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.