Evidence map›Paper›PMID 38124097›Full record

ArticleJournal of nanobiotechnology2023

A novel polymer enabled by polymerized small molecule strategy for tumor photothermal and photodynamic therapy.

Xin Xie, Ke Wang, Jie Zeng, Miao-Yan Xu, Xin-Hui Qu, Zheng-Bin Xiang, Fang-Fang Tou, Shaorong Huang, Xiao-Jian Han

Open access · goldAbstract read
In one paragraph

Article in Journal of nanobiotechnology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Xin XieSchool of Pharmacy, Jiangxi Medical College, Nanchang University, Nanchang, 330006, Jiangxi, People's Republic of China.
Ke WangDepartment of Clinical Laboratory, Jiangxi Provincial Children's Hospital, Nanchang, 330006, Jiangxi, People's Republic of China.
Jie ZengSchool of Pharmacy, Jiangxi Medical College, Nanchang University, Nanchang, 330006, Jiangxi, People's Republic of China.
Miao-Yan XuSchool of Pharmacy, Jiangxi Medical College, Nanchang University, Nanchang, 330006, Jiangxi, People's Republic of China.
Xin-Hui QuThe Second Department of Neurology, Jiangxi Provincial People's Hospital, The First Affiliated Hospital of Nanchang Medical College, Nanchang, 330006, Jiangxi, People's Republic of China.
Zheng-Bin XiangThe Second Department of Neurology, Jiangxi Provincial People's Hospital, The First Affiliated Hospital of Nanchang Medical College, Nanchang, 330006, Jiangxi, People's Republic of China.
Fang-Fang TouDepartment of Oncology, Jiangxi Provincial People's Hospital, The First Affiliated Hospital of Nanchang Medical College, Nanchang, 330006, Jiangxi, People's Republic of China.
Shaorong HuangSchool of Pharmacy, Jiangxi Medical College, Nanchang University, Nanchang, 330006, Jiangxi, People's Republic of China. huangshaorong@ncmc.edu.cn.
Xiao-Jian HanInstitute of Geriatrics, Jiangxi Provincial People's Hospital &, The First Affiliated Hospital of Nanchang Medical College, Nanchang, 330006, Jiangxi, People's Republic of China. hanxiaojian@hotmail.com.
First Affiliated Hospital of Jiangxi Medical College · CNJiangxi Provincial People's Hospital · CNNanchang University · CNJiangxi Provincial Children's Hospital · CN

Funding

National Natural Science Foundation of China 82060177Natural Science Foundation of Jiangxi Province 20224ACB206014Science and Technology Plan Project of Traditional Chinese Medicine of Jiangxi Province 2023A0148Science and Technology Plan Project of Traditional Chinese Medicine of Jiangxi Province 2023B0187Science and Technology Research Project of Education Department of Jiangxi Province GJJ2203553
6 · The paper itself

Abstract

Photothermal therapy (PTT) and photodynamic therapy (PDT) are effective method for tumor treatment. However, the limited variety and quantity of photothermal agents (PTAs) and photosensitizer (PSs) are still major challenges. Moreover, the cell apoptosis mechanism induced by PDT and PTT is still elusive. A fused-ring small molecule acceptor-donor acceptor' donor-acceptor (A-DA'D-A) type of Y5 (Scheme 1) has a narrow band-gap and strong light absorption. Herein, we used Y5 to polymerize with thiophene unit to obtain polymer PYT based on polymerized small molecule strategy, and PYT nanoparticles (PYT NPs) was prepared via one-step nanoprecipitation strategy with DSPE-PEG

Indexed as

NanoparticlesNeoplasmsPhotochemotherapyHumansPhotosensitizing AgentsPhototherapyPolymersPhotosensitizing AgentsPolymersFused-ring moleculePhotodynamic therapyPhotothermal therapyPolymerized small moleculeTumor treatment

Identifiers

PMID38124097
PMCPMC10734082
OpenAlexW4389993475

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.