Evidence map›Paper›PMID 38124038›Full record

ArticleBMC infectious diseases2023

The value of serum neutralizing antibody in evaluating predictability of COVID-19 after recovery and the validation of vaccine.

Bianqin Guo, Zheng Li, Gang Fu, Hong Li, Jing Yang, Zhenbin Zhang, Lixiang Wu, Jing Wang

Open access · goldAbstract read
In one paragraph

Article in BMC infectious diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 76% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Bianqin Guo *Department of Clinical Laboratory, Chongqing University Cancer Hospital & Chongqing Cancer Institute & Chongqing Cancer Hospital, Chongqing, China.
Zheng Li *Department of Clinical Laboratory, Chongqing University Cancer Hospital & Chongqing Cancer Institute & Chongqing Cancer Hospital, Chongqing, China.
Gang Fu *Department of Clinical Laboratory, Chongqing University Cancer Hospital & Chongqing Cancer Institute & Chongqing Cancer Hospital, Chongqing, China.
Hong LiDepartment of Clinical Laboratory, Chongqing University Cancer Hospital & Chongqing Cancer Institute & Chongqing Cancer Hospital, Chongqing, China.
Jing YangDepartment of Clinical Laboratory, Chongqing University Cancer Hospital & Chongqing Cancer Institute & Chongqing Cancer Hospital, Chongqing, China.
Zhenbin ZhangTianjin Enterprise Key Laboratory of Chemiluminescence and POCT Diagnostic Technology, Tianjin, China.
Lixiang WuDepartment of Clinical Laboratory, Chongqing University Cancer Hospital & Chongqing Cancer Institute & Chongqing Cancer Hospital, Chongqing, China. wlx124610@aliyun.com.
Jing WangDepartment of Clinical Laboratory, Chongqing Public Health Medical Treatment Center, Chongqing, China. oceanriverlake@163.com.
Chongqing Cancer Hospital · CNChongqing Public Health Medical Center · CN

Funding

Chongqing Natural Science Foundation Project cstc2021jcyj-msxmX1221the Coronavirus Disease 2019 Emergency Scientific Research Project of Chongqing University 2020CDJYGRH-1004the medical scientific research project of Chongqing Health Commission 2022WSJK037
6 · The paper itself

Abstract

backgroundThis work aimed to study natural humoral immune response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

methodsChemiluminescent immunoassay (CLIA) was used to detect the neutralizing antibody (Nabs) and IgG.

resultsNabs peaked on days 57-96 after symptom onset and remained detected on days 97-132. The Nabs in the 32 patients who were dynamically monitored showed four changing patterns. The titers of Nabs and IgG were correlated, and three modes of relationship were found between them.

conclusionsNabs showed a regular change in the course of coronavirus disease 2019 (COVID-19). The detection of Nabs is very important for monitoring the course of COVID-19 and predicting the strength of antibody protection.

Indexed as

COVID-19VaccinesAntibodies, NeutralizingHumansImmunoglobulin GSARS-CoV-2Antibodies, NeutralizingImmunoglobulin GVaccinesCOVID-19IgGNeutralizing antibodySARS‐CoV‐2

Identifiers

PMID38124038
PMCPMC10734152
OpenAlexW4389993365

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.