Evidence map›Paper›PMID 38124001›Full record

ArticleJournal of medical genetics2024

Risk-reducing decisions regarding germline

Akiko Abe, Hidetaka Nomura, Atsushi Fusegi, Mayu Yunokawa, Arisa Ueki, Eri Habano, Hiromi Arakawa, Keika Kaneko, Yuko Minoura, Hitoshi Inari and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of medical genetics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Akiko AbeCancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan akiko.abe@jfcr.or.jp.ORCID 0000-0003-0826-082X
Hidetaka NomuraCancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan.
Atsushi FusegiCancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan.
Mayu YunokawaCancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan.
Arisa UekiCancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan.
Eri HabanoCancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan.
Hiromi ArakawaCancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan.
Keika KanekoCancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan.
Yuko MinouraCancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan.
Hitoshi InariCancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan.
Takayuki UenoCancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan.
Hiroyuki KanaoCancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan.
Japanese Foundation For Cancer Research · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn Japan, the public insurance policy was revised in 2020 to cover hereditary breast and ovarian cancer (HBOC), including genetic testing and surveillance, for patients with breast cancer (BC). Consequently, the demand for risk-reducing salpingo-oophorectomy (RRSO) has increased. This study aimed to clarify the changes in the demand and timing of genetic testing and RRSO associated with public insurance coverage for HBOC in Japan.

methodsThis retrospective analysis included 350 women with germline

resultsThe findings indicate that RRSO rates doubled from 31.4% to 62.6% among patients with g

conclusionOverall, the insurance coverage for HBOC patients with BC has increased the frequency of RRSO in Japan. However, a comparison between the number of probands and family members indicated that the diagnosis among family members is inadequate. The inequality in the use of genetic services by socioeconomic groups is an issue of further concern.

Indexed as

Breast NeoplasmsOvarian NeoplasmsBRCA1 ProteinFemaleGenetic Predisposition to DiseaseGenetic TestingGerm CellsHumansMutationOvariectomyRetrospective StudiesSalpingo-oophorectomyBRCA1 Proteinwomen's health services

Identifiers

PMID38124001
PMCPMC10982634
OpenAlexW4389822923

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.