Evidence map›Paper›PMID 38123869›Full record

ArticleEJNMMI radiopharmacy and chemistry2023

Chromatographic separation of silver-111 from neutron-irradiated palladium target: toward direct labeling of radiotracers.

Marianna Tosato, Andrea Gandini, Steffen Happel, Marine Bas, Antonietta Donzella, Aldo Zenoni, Andrea Salvini, Alberto Andrighetto, Valerio Di Marco, Mattia Asti

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in EJNMMI radiopharmacy and chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Marianna TosatoRadiopharmaceutical Chemistry Section, Nuclear Medicine Unit, AUSL di Reggio Emilia: Azienda Unità Sanitaria Locale - IRCCS Tecnologie Avanzate e Modelli Assistenziali in Oncologia di Reggio Emilia, Via Amendola 2, 42122, Reggio Emilia, Italy.
Andrea GandiniLaboratory of Applied Nuclear Energy, 27100, Pavia, Italy.
Steffen HappelTrisKem International SAS, 35170, Brittany, France.
Marine BasTrisKem International SAS, 35170, Brittany, France.
Antonietta DonzellaDepartment of Mechanical and Industrial Engineering, University of Brescia, 25123, Brescia, Italy.
Aldo ZenoniDepartment of Mechanical and Industrial Engineering, University of Brescia, 25123, Brescia, Italy.
Andrea SalviniLaboratory of Applied Nuclear Energy, 27100, Pavia, Italy.
Alberto AndrighettoItalian Institute of Nuclear Physics, Legnaro National Laboratories, 35020, Legnaro, (Padova), Italy.
Valerio Di MarcoDepartment of Chemical Sciences, University of Padova, 35131, Padua, Italy.
Mattia AstiRadiopharmaceutical Chemistry Section, Nuclear Medicine Unit, AUSL di Reggio Emilia: Azienda Unità Sanitaria Locale - IRCCS Tecnologie Avanzate e Modelli Assistenziali in Oncologia di Reggio Emilia, Via Amendola 2, 42122, Reggio Emilia, Italy. asti.mattia@ausl.re.it.ORCID http://orcid.org/0000-0001-7564-7405
University of Padua · ITUniversity of Pavia · ITAzienda Sanitaria Unità Locale di Reggio Emilia · ITIstituto Nazionale di Fisica Nucleare, Laboratori Nazionali di Legnaro · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSilver-111 is a promising β

resultsA two-step sequence chromatographic process was validated for cold Ag-Pd separation and then translated to the radioactive counterpart. Silver-111 was produced via the

conclusionsThe developed separation method was suitable to obtain silver-111 with high molar activity in a ready-to-use water-based formulation that can be directly employed for the labeling of radiotracers. By successfully establishing a robust and efficient production and purification method for silver-111, this research paves the way for its wider application in targeted radionuclide therapy and precision imaging.

Indexed as

Nuclear reactorPalladium-110Radiochemical purificationRadionuclide productionSilver-111TheranosticTheranostic pair

Identifiers

PMID38123869
PMCPMC10733254
OpenAlexW4389991812

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.