Evidence map›Paper›PMID 38123799›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2024

Predictors of successful extubation from volume-targeted ventilation in extremely preterm neonates.

Dimitrios Rallis, Danielle Ben-David, Kendra Woo, Jill Robinson, David Beadles, Fotios Spyropoulos, Helen Christou, Sule Cataltepe

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07240038 (Evaluation of an Evidence Based, Bundled Intervention to Reduce Incidence of Ventilator-associated Pneumonia in Neonatal Units), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07240038 recruitingnot on this map

Evaluation of an Evidence Based, Bundled Intervention to Reduce Incidence of Ventilator-associated Pneumonia in Neonatal Units (INBERNAV-Neo)

Typeobservational_patient_registrySponsorBiobizkaia Health Research InstituteRan2024 to 2026Enrolled1,500ConditionsPneumonia Ventilator Associated, Pneumonia Neonatal, Healthcare-associated InfectionsArmsMultimodal intervention to reduce the incidence of ventilator-associated pneumonia by training the health care team in specific and general evidence-based good clinical practices., Technique with a blind-protected catheter
3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 2 countries.

Dimitrios RallisBrigham and Women's Hospital, Harvard Medical School, Boston, MA, USA. drallis@uoi.gr.ORCID 0000-0002-5156-0345
Danielle Ben-DavidBrigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Kendra WooBrigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Jill RobinsonBrigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
David BeadlesBrigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Fotios SpyropoulosBrigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-1663-9701
Helen ChristouBrigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-3104-4570
Sule CataltepeBrigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.ORCID 0000-0002-1459-3607
Brigham and Women's Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo identify variables associated with extubation success in extremely preterm neonates extubated from invasive volume-targeted ventilation. STUDY

designWe retrospectively evaluated 84 neonates ≤28 weeks' gestational age, on their first elective extubation. The primary outcome of successful extubation was defined as non-reintubation within seven days. We used multivariate logistic regression analysis.

resultsWe identified 58 (69%) neonates (mean gestational age of 26.5 ± 1.4 weeks, birthweight 921 ± 217 g) who met the primary outcome. Female sex (OR 1.15, 95% CI 1.01-9.10), higher pre-extubation weight (OR 1.29, 95% CI 1.05-1.59), and pH (OR 2.54, 95% CI 1.54-4.19), and lower pre-extubation mean airway pressure (MAP) (OR 0.49, 95% CI 0.33-0.73) were associated with successful extubation.

conclusionsIn preterm neonates, female sex, higher pre-extubation weight and pH, and lower pre-extubation MAP were predictors of successful extubation from volume-targeted ventilation. Evaluation of these variables will likely assist clinicians in selecting the optimal time for extubation in such vulnerable neonates.

Indexed as

Airway ExtubationInfant, Extremely PrematureFemaleHumansInfantInfant, NewbornRespirationRespiration, ArtificialRetrospective Studies

Identifiers

PMID38123799
OpenAlexW4389994787

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.