ArticleAnnals of intensive care2023
Individual response in patient's effort and driving pressure to variations in assistance during pressure support ventilation.
Article in Annals of intensive care, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.
- Noninvasive monitoring of inspiratory effort in mechanical ventilation: a dual-database bibliometric analysis from 1990 to 2025.Frontiers in medicine · 2025Pooled it
- ARDS management beyond the guidelines: a practical physiology-based approach to individualized care.Intensive care medicine · 2026Review
- Non-Invasive Respiratory Support in "De Novo" Acute Hypoxemic Respiratory Failure: Which Technique Is Best?Medicina (Kaunas, Lithuania) · 2026Review
- Effect of lateral positioning on ventilation in patients with blunt thoracic injury during pressure support ventilation: the VICTORY study.Intensive care medicine experimental · 2026Article
- Patient Self-Inflicted Lung Injury in ARDS: From Physiological Concept to Clinical Syndrome.Journal of clinical medicine · 2026Review
- STOP algorithm for bedside mechanical ventilation: Standardized, evidence-based management of critically ill patients.Biomolecules & biomedicine · 2026Article
- The invasive and non-invasive monitoring of inspiratory effort and drive during assisted mechanical ventilation.Annals of intensive care · 2026Review
- Assessment of V/Q mismatch during pressure support ventilation with electrical impedance tomography: a prospective physiological study.Intensive care medicine experimental · 2025Article
- Is Measurement of Inspiratory Effort and Respiratory Mechanics before Ventilator Weaning a Step toward Personalized Medicine?American journal of respiratory and critical care medicine · 2025Article
- A clinical guide to non-invasive respiratory support in acute respiratory failure: ventilation settings, technical optimization and clinical indications.Critical care (London, England) · 2025Review
- Mechanical power normalized to dynamic lung compliance as a predictor of weaning and prognosis in mechanically ventilated patients: a retrospective cohort study.BMC anesthesiology · 2025Observational
- Assessing inspiratory drive and effort in critically ill patients at the bedside.Critical care (London, England) · 2025Review
- Noninvasive ventilation in acute hypoxemic respiratory failure: What is the future?Journal of intensive medicine · 2025Review
- Advanced serial analysis of the diaphragm surface EMG: insights into the effect of pressure support on the neuro-ventilatory response during the ICU stay.Critical care (London, England) · 2025Article
- Bedside Assessment of the Respiratory System During Invasive Mechanical Ventilation.Journal of clinical medicine · 2024Review
- Pressure support, patient effort and tidal volume: a conceptual model for a non linear interaction.Critical care (London, England) · 2024Review
- Use of pressure muscle index to predict the contribution of patient's inspiratory effort during pressure support ventilation: a prospective physiological study.Frontiers in medicine · 2024Article
- A cluster randomized trial on inspiratory effort-targeted pressure support adjustment strategy in patients undergoing assisted mechanical ventilation: protocol for the IT-PSV study.Frontiers in medicine · 2024Article
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDuring Pressure Support Ventilation (PSV) an inspiratory hold allows to measure plateau pressure (Pplat), driving pressure (∆P), respiratory system compliance (Crs) and pressure-muscle-index (PMI), an index of inspiratory effort. This study aims [1] to assess systematically how patient's effort (estimated with PMI), ∆P and tidal volume (Vt) change in response to variations in PSV and [2] to confirm the robustness of Crs measurement during PSV.
methods18 patients recovering from acute respiratory failure and ventilated by PSV were cross-randomized to four steps of assistance above (+ 3 and + 6 cmH
resultsAs PSV was decreased, Pplat (from 20.5 ± 3.3 cmH
conclusionPatients react to a decrease in PSV by increasing inspiratory effort-as estimated by PMI-keeping Vt and ∆P on a desired value, therefore, limiting the clinician's ability to modulate them. PMI appears a valuable index to assess the point of ventilatory overassistance when patients lose control over Vt like in a pressure-control mode. The measurement of Crs in PSV is constant-likely suggesting reliability-independently from the level of assistance and patient's effort.
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