Evidence map›Paper›PMID 38123748›Full record

ArticleSpinal cord2024

Risk factors of major complications after flap surgery in the treatment of stage III and IV pressure injury in people with spinal cord injury/disorder: a retrospective cohort study.

Carina Fähndrich, Armin Gemperli, Michael Baumberger, Michael Harder, Bianca Roth, Dirk J Schaefer, Reto Wettstein, Anke Scheel-Sailer

Registry-linked trialOpen access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Spinal cord, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06441721 (Vitamin b12 Deficency and Its Impact on Chronic Haemodialysis Patient and Its Effect on Anemia and Neuropathy), which is not on this map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06441721 unknown statusnot on this map

Vitamin b12 Deficency and Its Impact on Chronic Haemodialysis Patient and Its Effect on Anemia and Neuropathy

TypeobservationalSponsorAssiut UniversityRan2024 to 2025Enrolled60ConditionsEnd Stage Renal Disease on Dialysis, Vitamin B 12 DeficiencyArmsVitamin b12 measure
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Carina FähndrichSwiss Paraplegic Research, Nottwil, Switzerland. carina.faehndrich@paraplegie.ch.ORCID 0009-0002-5359-5047
Armin GemperliFaculty of Health Sciences and Medicine, University of Lucerne, Lucerne, Switzerland.
Michael BaumbergerSwiss Paraplegic Centre, Nottwil, Switzerland.ORCID 0000-0002-7296-0495
Michael HarderSwiss Paraplegic Centre, Nottwil, Switzerland.
Bianca RothDepartment of Infectious diseases, Cantonal Hospital Lucerne, Lucerne, Switzerland.
Dirk J SchaeferDepartment of Plastic, Reconstructive, Aesthetic and Hand Surgery, University Hospital of Basel, Basel, Switzerland.
Reto WettsteinDepartment of Plastic, Reconstructive, Aesthetic and Hand Surgery, University Hospital of Basel, Basel, Switzerland.
Anke Scheel-SailerFaculty of Health Sciences and Medicine, University of Lucerne, Lucerne, Switzerland.ORCID 0000-0003-3820-6664
University of Lucerne · CHSwiss Paraplegic Research · CHUniversity Hospital of Basel · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designRetrospective cohort study.

objectivesTo identify risk factors associated with major complications after flap surgery in people with spinal cord injury or disorder (SCI/D) and stage III and IV pressure injury (PI).

settingSwiss hospital specialized in the treatment of people with SCI/D using the Basel Decubitus Approach.

methodsWe examined 60 risk factors for major postoperative complications in PIs over sacrum/coccyx, ischium or trochanter between 01/2016 and 12/2021. We performed descriptive analysis and computed global p-values using likelihood ratio tests adjusted for clustering of PIs in individuals.

resultsWe included 220 PI treatment procedure from 149 individuals. The study population consisted of 163 (74%) men, 133 (60%) traumatic SCI, 136 (58%) stage IV PI, 198 (90%) individuals with paraplegia, 93 (42%) with osteomyelitis, and 85 (39%) with recurrent PI. Major complications 42 (19%) occurred more often in individuals with stage IV PI (p < 0.01), individuals without osteomyelitis (p < 0.03), and individuals with pathological blood concentrations of cystatin c (p < 0.028), calcium (p < 0.048), and vitamin B12 (p < 0.0049) as well as normal blood concentrations of HbA1c (p < 0.033). Immobilization (p < 0.0089) and hospital stay (p < 0.0001) of individuals with major complications was longer.

conclusionIn the Basel Decubitus Approach, stage IV PI, absence of osteomyelitis, reduced vitamin B12 and calcium, elevated cystatin c, and normal HbA1c should be addressed to reduce major complications.

Indexed as

OsteomyelitisPressure UlcerSpinal Cord InjuriesCalciumCystatin CFemaleGlycated HemoglobinHumansMaleRetrospective StudiesRisk FactorsVitamin B 12CalciumCystatin CGlycated HemoglobinVitamin B 12

Identifiers

PMID38123748
PMCPMC10783547
OpenAlexW4389993460

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.