Evidence map›Paper›PMID 38123711›Full record

ReviewPediatric nephrology (Berlin, Germany)2024

Kidney biopsy findings in children with diabetes mellitus.

Lasanthi Weerasooriya, Alexander J Howie, Matthew P Wakeman, Susan Cavanagh, David V Milford

Open access · hybridAbstract readReview
In one paragraph

Review in Pediatric nephrology (Berlin, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Susceptibility to diabetic nephropathy.Pediatric nephrology (Berlin, Germany) · 2024
    Article
  3. Response to "Susceptibility to diabetic nephropathy".Pediatric nephrology (Berlin, Germany) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Lasanthi WeerasooriyaDepartment of Nephrology, Birmingham Children's Hospital, Birmingham, B4 6NH, UK.
Alexander J HowieDepartment of Histopathology, Birmingham Children's Hospital, Birmingham, B4 6NH, UK. alexander.howie@nhs.net.ORCID 0000-0003-4179-9480
Matthew P WakemanDepartment of Histopathology, Birmingham Children's Hospital, Birmingham, B4 6NH, UK.
Susan CavanaghDepartment of Histopathology, Birmingham Children's Hospital, Birmingham, B4 6NH, UK.
David V MilfordDepartment of Nephrology, Birmingham Children's Hospital, Birmingham, B4 6NH, UK.
Birmingham Children's Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiabetic nephropathy may begin in childhood, but clinical kidney disease ascribable to this is uncommon in children with type 1 (insulin dependent) diabetes mellitus.

methodsWe reviewed our experience of kidney biopsies in children with type 1 diabetes mellitus.

resultsBetween 1995 and 2022, there were biopsies in 17 children, with various clinical indications for kidney biopsy, making this the largest series of biopsies in diabetic children with clinical kidney abnormalities. Four biopsies showed diabetic nephropathy, three showed the combination of diabetic nephropathy and IgA nephropathy, and ten showed a variety of conditions other than diabetic nephropathy: minimal change disease (2), membranous nephropathy (2), thin glomerular basement membrane lesion (2), non-glomerular chronic damage in Wolcott-Rallison syndrome (2), acute pauciimmune necrotizing crescentic glomerulonephritis (1) and IgA nephropathy (1). Clinical clues of something other than diabetic nephropathy included acute kidney injury, microscopic haematuria or chronic kidney impairment with little or no proteinuria and the nephrotic syndrome after a short duration of diabetes.

conclusionsWe confirm that changes better known in adults with either type 1 or type 2 diabetes mellitus can occur in children with type 1 diabetes mellitus: overt diabetic nephropathy either on its own or combined with other conditions and kidney disorders other than diabetic nephropathy.

Indexed as

Diabetes Mellitus, Type 1Diabetes Mellitus, Type 2Diabetic NephropathiesGlomerulonephritis, IGAKidney DiseasesAdultBiopsyChildHumansKidneyProteinuriaDiabetes mellitusDiabetic nephropathyKidney biopsy

Identifiers

PMID38123711
PMCPMC11026184
OpenAlexW4390024925

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.