Evidence map›Paper›PMID 38123697›Full record

ArticleLeukemia2024

Backtracking to the future: unraveling the origins of childhood leukemia.

Adam J de Smith, Joseph L Wiemels, Adam J Mead, Irene Roberts, Anindita Roy, Logan G Spector

Abstract read
In one paragraph

Article in Leukemia, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Biomedicines · 2025
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Adam J de SmithCenter for Genetic Epidemiology, Department of Population and Public Health Sciences, University of Southern California Keck School of Medicine, Los Angeles, CA, USA. desmith@usc.edu.ORCID http://orcid.org/0000-0003-4880-7543
Joseph L WiemelsCenter for Genetic Epidemiology, Department of Population and Public Health Sciences, University of Southern California Keck School of Medicine, Los Angeles, CA, USA.ORCID http://orcid.org/0000-0003-4838-9951
Adam J MeadHaematopoietic Stem Cell Biology Laboratory, MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0001-8522-1002
Irene RobertsDepartment of Paediatrics and MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.
Anindita RoyDepartment of Paediatrics and MRC Molecular Haematology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0001-8607-5748
Logan G SpectorDivision of Epidemiology and Clinical Research, Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, MN, USA. spector@umn.edu.

Funding

Backtracking Leukemia-Typical Somatic Alterations in Cord Blood at Single-cell ResolutionR01CA262012 · NCI · UNIVERSITY OF MINNESOTA · PI DE SMITH, ADAM, SPECTOR, LOGAN G. · 2021 to 2025
$2.9M
Genomics of childhood acute lymphoblastic leukemia in the Childhood Cancer and Leukemia International ConsortiumR01CA266253 · NCI · UNIVERSITY OF MINNESOTA · PI Saonli Basu, Logan G. Spector · 2022 to 2026
$2.9M
Variant to Function Mapping of B-ALL Risk LociR01CA292941 · NCI · BOSTON CHILDREN'S HOSPITAL · PI Adam De Smith, Vijay Ganesh Sankaran · 2024 to 2026
$2.0M
Medical Research Council MC_UU_00029/7NCI NIH HHS R01 CA262012NCI NIH HHS R01 CA266253NCI NIH HHS R01 CA292941Wellcome Trust 216632/Z/19/Z
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

LeukemiaChildHumans

Identifiers

PMID38123697
PMCPMC11092887

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.