ArticleNature2024
Mitochondrial dysfunction abrogates dietary lipid processing in enterocytes.
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Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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0cells of the map it votes in
39citing papers in PubMed
11.2field-weighted citation impact, top 1% of its field
What it found
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Who cites it
39 citing papers in PubMed, 61 citations in OpenAlex.
- A targeted lipidomics workflow for high-throughput phenotyping and mechanism-based in vitro hepatotoxicity studies.Toxicology in vitro : an international journal published in association with BIBRA · 2026Article
- Inhibiting menin attenuates high-fat diet-induced weight gain by limiting intestinal lipid absorption in mice.The Journal of clinical investigation · 2026Article
- Stable Isotope-Resolved Metabolomics in Elucidating Mitochondrial Metabolic Reprogramming and Therapeutic Targets.Biomedical chromatography : BMC · 2026Review
- From Gut to Fat: Intestinal Epithelial Exosomes Target PDGFRαAging cell · 2026Article
- A plant vesicle-dendritic cell chimera for enhancing cancer immunotherapy.Nature communications · 2026Article
- Alkaloids from Dendrobium Nobile Lindl Improves Mitochondrial Function by Enhancing the Activity of v-ATPase in APP/PS1 Mice.Neurochemical research · 2026Article
- DENND5B disruption results in reduced body fat and increased intestinal fatty acid oxidation by activation of autophagy.Journal of lipid research · 2026Article
- Dynamic collaboration between mitochondria and organelles: mechanisms, functions, and disease implications.Apoptosis : an international journal on programmed cell death · 2026Review
- Age-Related Decline in Intestinal Villus Length: A Cross-Sectional Study on the Human Gut.Nutrients · 2026Observational
- Enterocytes rely on purine biosynthesis/salvage pathway to facilitate dietary fat absorption.Nature communications · 2026Article
- A genetic screen in enteroendocrine cells reveals mechanisms that control protein sensing and GLP-1 release.bioRxiv : the preprint server for biology · 2026Article
- The role of metabolic crosstalk between Intestinal epithelial cells and immune cells in inflammatory bowel disease and targeting strategies.Frontiers in immunology · 2026Review
- Gut Microbiota-Derived Tyrosol Alleviates Radiation-Induced Intestinal Injury via Targeting SCD1-MUFA Axis to Suppress ER Stress.International journal of biological sciences · 2026Article
- Microbial metabolite indole-3-propionic acid drives mitochondrial respiration in CD4Nature metabolism · 2025Article
- Ambient light alleviates retinal neurodegeneration in mice by powering mitochondria via the engineered optoenergetic rhodopsin.Signal transduction and targeted therapy · 2025Article
- Healthy mitochondria attenuate metabolic dysfunction-associated steatohepatitis by restoring cell metabolism.Molecular biomedicine · 2025Article
- The intervention of NLRP3 inflammasome inhibitor: oridonin against azoxymethane and dextran sulfate sodium-induced colitis-associated colorectal cancer in male BALB/c mice.Naunyn-Schmiedeberg's archives of pharmacology · 2025Article
- Strain-specific responses to dextran sulfate sodium-induced ulcerative colitis in BALB/c and C57BL/6 mice: Comparative analysis of local versus extra-intestinal manifestations.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025Article
- Gut microbiota-mediated lipid accumulation as a driver of evolutionary adaptation to blue light toxicity in Drosophila.Communications biology · 2025Article
- eIF5A maintains intestinal epithelial homeostasis by sustaining intestinal stem cells.Cell regeneration (London, England) · 2025Article
Corrections and comments
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Authors and funding
21 authors at 4 institutions in 2 countries.
Chrysanthi MoschandreaInstitute for Genetics, University of Cologne, Cologne, Germany.
Vangelis KondylisInstitute for Pathology, Medical Faculty and University Hospital of Cologne, University of Cologne, Cologne, Germany.ORCID 0000-0002-6970-8731
Ioannis EvangelakosDepartment of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.ORCID 0000-0001-7328-6319
Marija HerholzCologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.
Farina SchneiderCologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.
Christina SchmidtCologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.
Ming YangCologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.
Sandra EhretDepartment of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Markus HeineDepartment of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Michelle Y JaecksteinDepartment of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Karolina SzczepanowskaCologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.
Robin SchwarzerInstitute for Genetics, University of Cologne, Cologne, Germany.
Linda BaumannCologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.
Theresa BockInstitute for Genetics, University of Cologne, Cologne, Germany.ORCID 0000-0002-8308-4021
Efterpi NikitopoulouMRC Cancer Unit, University of Cambridge, Hutchison/MRC Research Centre, Cambridge Biomedical Campus, Cambridge, UK.
Susanne BrodesserCologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.ORCID 0000-0001-5631-0663
Marcus KrügerInstitute for Genetics, University of Cologne, Cologne, Germany.
Christian FrezzaCologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.ORCID 0000-0002-3293-7397
Joerg HeerenDepartment of Biochemistry and Molecular Cell Biology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.ORCID 0000-0002-5647-1034
Aleksandra TrifunovicCologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany. atrifuno@uni-koeln.de.ORCID 0000-0002-5472-3517
Manolis PasparakisInstitute for Genetics, University of Cologne, Cologne, Germany. pasparakis@uni-koeln.de.ORCID 0000-0002-9870-0966
University of Cologne · DEUniversität Hamburg · DETH Köln - University of Applied Sciences · DEUniversity of Cambridge · GB
Funding
Northwestern University Clinical & Translational Sciences Institute (NUCATS) 2.0U54TR001018 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI LLOYD-JONES, DONALD M · 2014 to 2014
$4.2MNCATS NIH HHS U54 TR001018
Abstract
Digested dietary fats are taken up by enterocytes where they are assembled into pre-chylomicrons in the endoplasmic reticulum followed by transport to the Golgi for maturation and subsequent secretion to the circulation
Indexed as
Dietary FatsEnterocytesLipid MetabolismMitochondriaAlkyl and Aryl TransferasesAnimalsAspartate-tRNA LigaseChylomicronsElectron Transport Complex IIEndoplasmic ReticulumEpithelial CellsGolgi ApparatusIntestinesLipid DropletsMembrane ProteinsMiceAlkyl and Aryl TransferasesAspartate-tRNA LigaseChylomicronsCOX10 protein, mouseDietary FatsElectron Transport Complex IIMembrane Proteins
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.