ArticleNature2024
RNA-mediated symmetry breaking enables singular olfactory receptor choice.
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Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
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36citing papers in PubMed
10.0field-weighted citation impact, top 1% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
36 citing papers in PubMed, 49 citations in OpenAlex.
- CXCR4 Coordinates Long-Term Olfactory Epithelial Regeneration and Cellular Stress Response After Injury.Molecular neurobiology · 2026Article
- Autosomal allelic inactivation at loci with variable replication timing and dosage sensitivity.eLife · 2026Article
- A spatial code governs olfactory receptor choice and aligns sensory maps in the nose and brain.Cell · 2026Article
- Metadomain and metaloop genome interactions in mammalian T cells.Cell reports · 2026Article
- A single-cell and spatial atlas of early human olfactory development.Nature communications · 2026Article
- Novel mechanisms of chemosensory adaptation to the cave environment.bioRxiv : the preprint server for biology · 2026Article
- Delta family protocadherins contribute to protoglomerular targeting of olfactory sensory neuron axons in the olfactory bulb.PLoS genetics · 2026Article
- HP1β and H3K9me3 Regulate Olfactory Receptor Choice and Transcriptional Identity.International journal of molecular sciences · 2026Article
- iceDP: identifying inter-chromatin engagement via density peaks clustering algorithm.Briefings in bioinformatics · 2026Article
- Extra-nasal odorant receptors: molecular mechanisms and therapeutic implications.Frontiers in physiology · 2026Review
- The Quartet of Core Oncogenic Drivers in Neuroendocrine Prostate Cancer: Multi-Omics Dataset Integration to Forge a Translational Link Between Biology and Precision Therapy.International journal of biological sciences · 2026Review
- 3D genome folding in epigenetic regulation and cellular memory.Trends in cell biology · 2026Review
- An epigenetic repressor TRIM66 dictates monogenic olfactory receptor expression, neural activity, and olfactory behavior.Nature communications · 2025Article
- Tex15 is required for vomeronasal sensory neuron diversity and male pheromone detection.bioRxiv : the preprint server for biology · 2025Article
- Article
- Transcriptional interference gates monogenic odorant receptor expression in ants.Current biology : CB · 2025Article
- A non-coding role for trypanosome VSG transcripts in allelic exclusion.Nucleic acids research · 2025Article
- Chromatin-associated condensates as an inspiration for the system architecture of future DNA computers.Annals of the New York Academy of Sciences · 2025Review
- Mex3a-dependent post-transcriptional silencing ensures olfactory receptor diversity and axon guidance specificity.Cell reports · 2025Article
- HP1β and H3K9me3 Regulate Olfactory Receptor Choice and Transcriptional Identity.bioRxiv : the preprint server for biology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 5 institutions in 2 countries.
Ariel D PourmoradyVagelos College of Physicians and Surgeons, Columbia University New York, New York, NY, USA.
Elizaveta V BashkirovaMortimer B. Zuckerman Mind, Brain, and Behavior Institute, Columbia University New York, New York, NY, USA.
Andrea M ChiarielloDepartment of Physics 'Ettore Pancini', University of Naples, and INFN, Napoli, Italy.ORCID 0000-0002-6112-0167
Houda BelagzhalDepartment of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA, USA.
Albana KodraIntegrated Program in Cellular, Molecular and Biomedical Studies, Vagelos College of Physicians and Surgeons, New York, NY, USA.
Rachel DuffiéMortimer B. Zuckerman Mind, Brain, and Behavior Institute, Columbia University New York, New York, NY, USA.ORCID 0000-0001-8529-1377
Jerome KahiapoDepartment of Molecular Biology & Biochemistry, Rutgers School of Arts and Sciences, Robert Wood Johnson Medical School, Piscataway, NJ, USA.
Kevin MonahanDepartment of Molecular Biology & Biochemistry, Rutgers School of Arts and Sciences, Robert Wood Johnson Medical School, Piscataway, NJ, USA.ORCID 0000-0001-8922-5801
Joan PulupaMortimer B. Zuckerman Mind, Brain, and Behavior Institute, Columbia University New York, New York, NY, USA.
Ira SchierenMortimer B. Zuckerman Mind, Brain, and Behavior Institute, Columbia University New York, New York, NY, USA.
Alexa OsterhoudtMortimer B. Zuckerman Mind, Brain, and Behavior Institute, Columbia University New York, New York, NY, USA.ORCID 0000-0002-1052-2473
Job DekkerDepartment of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA, USA.ORCID 0000-0001-5631-0698
Mario NicodemiDepartment of Physics 'Ettore Pancini', University of Naples, and INFN, Napoli, Italy.ORCID 0000-0002-8416-6416
Stavros LomvardasMortimer B. Zuckerman Mind, Brain, and Behavior Institute, Columbia University New York, New York, NY, USA. sl682@cumc.columbia.edu.ORCID 0000-0002-7668-3026
Columbia University · USIstituto Nazionale di Fisica Nucleare, Sezione di Napoli · ITRutgers, The State University of New Jersey · USUniversity of Massachusetts Chan Medical School · USSage Colleges · US
Funding
Structural Annotation of the Human GenomeR01HG003143 · NHGRI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI Job Dekker · 2003 to 2026
$15.4MCenter for 3D Structure and Physics of the GenomeUM1HG011536 · NHGRI · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI DEKKER, JOB, MIRNY, LEONID A · 2020 to 2024
$11.8MCenter for Integrated Multi-modal and Multi-scale Nucleome ResearchUM1HG011585 · NHGRI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DULAC, CATHERINE, LEIN, ED · 2020 to 2024
$6.7MOlfactory receptor mRNAs as lncRNAs that regulate genomic interactionsR01DC018744 · NIDCD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Stavros Lomvardas · 2020 to 2026
$3.7MInterrogating genome folding trajectories in health and diseaseU01DA052783 · NIDA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI LOMVARDAS, STAVROS · 2020 to 2024
$3.1MDeciphering mechanisms for olfactory receptor choice in single cellsF30DC020900 · NIDCD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI POURMORADY, ARIEL DAVID · 2022 to 2024
$148kDevelopmentally dynamic chromatin architecture during neurogenesisF31DC016785 · NIDCD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI HORTA, ADAN · 2017 to 2019
$137kNHGRI NIH HHS R01 HG003143NHGRI NIH HHS UM1 HG011536NHGRI NIH HHS UM1 HG011585NIDA NIH HHS U01 DA052783NIDCD NIH HHS F30 DC020900NIDCD NIH HHS F31 DC016785NIDCD NIH HHS R01 DC018744
Abstract
Olfactory receptor (OR) choice provides an extreme example of allelic competition for transcriptional dominance, where every olfactory neuron stably transcribes one of approximately 2,000 or more OR alleles
Indexed as
Olfactory Receptor NeuronsReceptors, OdorantRNAAllelesCell LineageEnhancer Elements, GeneticGene Expression RegulationGenomicsRegulatory Sequences, Nucleic AcidSingle-Cell AnalysisTranscription, GeneticReceptors, OdorantRNA
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.