Evidence map›Paper›PMID 38123676›Full record

ArticleNature2024

Structures of the promoter-bound respiratory syncytial virus polymerase.

Dongdong Cao, Yunrong Gao, Zhenhang Chen, Inesh Gooneratne, Claire Roesler, Cristopher Mera, Paul D'Cunha, Anna Antonova, Deepak Katta, Sarah Romanelli and 5 more

Open access · hybridAbstract read
In one paragraph

Article in Nature, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
9.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 46 citations in OpenAlex.

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  12. Structural insights into the dynamic mechanism of bornavirus polymerase.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Dongdong CaoDepartment of Biochemistry, Emory University School of Medicine, Atlanta, GA, USA.ORCID 0000-0002-2031-9321
Yunrong GaoDepartment of Biochemistry, Emory University School of Medicine, Atlanta, GA, USA.ORCID 0000-0001-6787-2397
Zhenhang ChenDepartment of Biochemistry, Emory University School of Medicine, Atlanta, GA, USA.
Inesh GooneratneDepartment of Biochemistry, Emory University School of Medicine, Atlanta, GA, USA.ORCID 0009-0006-3403-6687
Claire RoeslerDepartment of Biochemistry, Emory University School of Medicine, Atlanta, GA, USA.
Cristopher MeraDepartment of Biochemistry, Emory University School of Medicine, Atlanta, GA, USA.
Paul D'CunhaDepartment of Biochemistry, Emory University School of Medicine, Atlanta, GA, USA.
Anna AntonovaDepartment of Biochemistry, Emory University School of Medicine, Atlanta, GA, USA.
Deepak KattaDepartment of Biochemistry, Emory University School of Medicine, Atlanta, GA, USA.
Sarah RomanelliDepartment of Biochemistry, Emory University School of Medicine, Atlanta, GA, USA.
Qi WangDepartment of Biochemistry, Emory University School of Medicine, Atlanta, GA, USA.
Samantha RiceDepartment of Biochemistry, Emory University School of Medicine, Atlanta, GA, USA.
Wesley LemonsDepartment of Biochemistry, Emory University School of Medicine, Atlanta, GA, USA.
Anita RamanathanDepartment of Biochemistry, Emory University School of Medicine, Atlanta, GA, USA.
Bo LiangDepartment of Biochemistry, Emory University School of Medicine, Atlanta, GA, USA. bo.liang@emory.edu.ORCID 0000-0002-5617-9228
Emory University · US

Funding

NCCAT: National Center for CryoEM Access and Training- Supplement for Windows 10 and FFIU24GM129539 · NIGMS · NEW YORK STRUCTURAL BIOLOGY CENTER · PI DE MARCO, ALEX, KIEFT, JEFFREY S · 2018 to 2023
$53.9M
The Southeastern Consortium for Microscopy of MacroMolecular MachinesU24GM116788 · NIGMS · FLORIDA STATE UNIVERSITY · PI AGBANDJE-MCKENNA, MAVIS, BULLITT, ESTHER · 2016 to 2020
$4.6M
Midwest Consortium for High Resolution Cryoelectron MicroscopyU24GM116789 · NIGMS · PURDUE UNIVERSITY · PI BULLITT, ESTHER, DAI, WEI · 2017 to 2021
$3.5M
Structure and Regulation of The Respiratory Syncytial Virus PolymeraseR01GM130950 · NIGMS · EMORY UNIVERSITY · PI Bo Liang · 2019 to 2026
$3.3M
NIGMS NIH HHS R01 GM130950NIGMS NIH HHS U24 GM116788NIGMS NIH HHS U24 GM116789NIGMS NIH HHS U24 GM129539
6 · The paper itself

Abstract

The respiratory syncytial virus (RSV) polymerase is a multifunctional RNA-dependent RNA polymerase composed of the large (L) protein and the phosphoprotein (P). It transcribes the RNA genome into ten viral mRNAs and replicates full-length viral genomic and antigenomic RNAs

Indexed as

Promoter Regions, GeneticRespiratory Syncytial Virus, HumanRNA-Dependent RNA PolymeraseCryoelectron MicroscopyRNA, ViralSubgenomic RNAVirus ReplicationRNA-Dependent RNA PolymeraseRNA, ViralSubgenomic RNA

Identifiers

PMID38123676
PMCPMC10794133
OpenAlexW4389991859

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.