Evidence map›Paper›PMID 38123235›Full record

ReviewEuropean respiratory review : an official journal of the European Respiratory Society2023

Selection of potential targets for stratifying congenital pulmonary airway malformation patients with molecular imaging: is MUC1 the one?

Cathy van Horik, Marius J P Zuidweg, Anne Boerema-de Munck, Marjon Buscop-van Kempen, Erwin Brosens, Alexander L Vahrmeijer, Jan H von der Thüsen, René M H Wijnen, Robbert J Rottier, Willemieke S F J Tummers and 1 more

Open access · diamondAbstract readReview
In one paragraph

Review in European respiratory review : an official journal of the European Respiratory Society, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. The Diagnostics and Management of Bronchopulmonary Sequestration: An International Survey among Specialized Caregivers.European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Cathy van HorikDepartment of Pediatric Surgery, Erasmus Medical Center, Sophia Children's Hospital, Rotterdam, The Netherlands.ORCID https://orcid.org/0000-0003-2585-1197
Marius J P ZuidwegDepartment of Pediatric Surgery, Erasmus Medical Center, Sophia Children's Hospital, Rotterdam, The Netherlands.
Anne Boerema-de MunckDepartment of Pediatric Surgery, Erasmus Medical Center, Sophia Children's Hospital, Rotterdam, The Netherlands.
Marjon Buscop-van KempenDepartment of Pediatric Surgery, Erasmus Medical Center, Sophia Children's Hospital, Rotterdam, The Netherlands.
Erwin BrosensDepartment of Clinical Genetics, Erasmus Medical Center, Sophia Children's Hospital, Rotterdam, The Netherlands.
Alexander L VahrmeijerDepartment of Surgery, Leiden University Medical Center, Leiden, The Netherlands.
Jan H von der ThüsenDepartment of Pathology, Erasmus Medical Center, Rotterdam, The Netherlands.ORCID https://orcid.org/0000-0001-9699-4860
René M H WijnenDepartment of Pediatric Surgery, Erasmus Medical Center, Sophia Children's Hospital, Rotterdam, The Netherlands.
Robbert J RottierDepartment of Pediatric Surgery, Erasmus Medical Center, Sophia Children's Hospital, Rotterdam, The Netherlands.ORCID https://orcid.org/0000-0002-9291-4971
Willemieke S F J TummersDepartment of Surgery, Leiden University Medical Center, Leiden, The Netherlands.
J Marco SchnaterDepartment of Pediatric Surgery, Erasmus Medical Center, Sophia Children's Hospital, Rotterdam, The Netherlands j.schnater@erasmusmc.nl.ORCID https://orcid.org/0000-0003-4910-8293
Erasmus MC - Sophia Children’s Hospital · NLErasmus MC · NLLeiden University Medical Center · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Currently there is a global lack of consensus about the best treatment for asymptomatic congenital pulmonary airway malformation (CPAM) patients. The somatic KRAS mutations commonly found in adult lung cancer combined with mucinous proliferations are sometimes found in CPAM. For this risk of developing malignancy, 70% of paediatric surgeons perform a resection for asymptomatic CPAM. In order to stratify these patients into high- and low-risk groups for developing malignancy, a minimally invasive diagnostic method is needed, for example targeted molecular imaging. A prerequisite for this technique is a cell membrane bound target. The aim of this study was to review the literature to identify potential targets for molecular imaging in CPAM patients and perform a first step to validate these findings.A systematic search was conducted to identify possible targets in CPAM and adenocarcinoma

Indexed as

Cystic Adenomatoid Malformation of Lung, CongenitalLung NeoplasmsAdultChildDiagnostic ImagingHumansLungMucin-1Proto-Oncogene Proteins p21(ras)MUC1 protein, humanMucin-1Proto-Oncogene Proteins p21(ras)

Identifiers

PMID38123235
PMCPMC10754420
OpenAlexW4390031599

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.