Evidence map›Paper›PMID 38123150›Full record

ArticleBritish journal of pharmacology2023

The Concise Guide to PHARMACOLOGY 2023/24: Ion channels.

Stephen P H Alexander, Alistair A Mathie, John A Peters, Emma L Veale, Jörg Striessnig, Eamonn Kelly, Jane F Armstrong, Elena Faccenda, Simon D Harding, Jamie A Davies and 63 more

Abstract read
In one paragraph

Article in British journal of pharmacology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
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  6. Review
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  8. Article
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  14. Article
  15. GLP-1 agonists and the gut microbiome: A bidirectional relationship.British journal of clinical pharmacology · 2026
    Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article

13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

73 authors.

Stephen P H AlexanderSchool of Life Sciences, University of Nottingham Medical School, Nottingham, NG7 2UH, UK.ORCID 0000-0003-4417-497X
Alistair A MathieSchool of Engineering, Arts, Science and Technology, University of Suffolk, Ipswich, IP4 1QJ, UK.ORCID 0000-0001-6094-2890
John A PetersNeurosci-ence Division, Medical Education Institute, Ninewells Hospital and Medical School, University of Dundee, Dundee, DD1 9SY, UK.ORCID 0000-0002-4277-4245
Emma L VealeMedway School of Pharmacy, The Universities of Greenwich and Kent at Medway, Anson Building, Central Avenue, Chatham Maritime, Chatham, Kent, ME4 4TB, UK.ORCID 0000-0002-6778-9929
Jörg StriessnigPharmacology and Toxicology, Institute of Pharmacy, University of Innsbruck, A-6020, Innsbruck, Austria.ORCID 0000-0002-9406-7120
Eamonn KellySchool of Physiology, Pharmacology and Neuroscience, University of Bristol, Bristol, BS8 1TD, UK.
Jane F ArmstrongCentre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, EH8 9XD, UK.ORCID 0000-0002-0524-0260
Elena FaccendaCentre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, EH8 9XD, UK.ORCID 0000-0001-9855-7103
Simon D HardingCentre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, EH8 9XD, UK.ORCID 0000-0002-9262-8318
Jamie A DaviesCentre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, EH8 9XD, UK.ORCID 0000-0001-6660-4032
Richard W AldrichStanford University, Austin, USA.ORCID 0000-0001-7254-5876
Bernard AttaliTel Aviv University, Tel Aviv, Israel.ORCID 0000-0003-1066-7047
Austin M BaggettaNortheastern University, Boston, USA.ORCID 0000-0003-0852-1807
Elvir BecirovicLudwig Maximilian University of Munich, Munich, Germany.ORCID 0000-0001-8801-0649
Martin BielLudwig Maximilian University of Munich, Munich, Germany.ORCID 0000-0002-9974-3052
Roslyn M BillAston University, Birmingham, UK.ORCID 0000-0003-1331-0852
Ana I CaceresDuke University, Durham, USA.
William A CatterallUniversity of Washington, Seattle, USA.ORCID 0000-0001-5509-3580
Alex C ConnerUniversity of Birmingham, Birmingham, UK.ORCID 0000-0003-1539-5554
Paul DaviesTufts University School of Medicine, Boston, USA.
Katrien De ClerqCatholic University of Leuven, Leuven, Belgium.
Markus DellingUniversity of California San Francisco, San Francisco, USA.ORCID 0000-0001-9556-2097
Francesco Di VirgilioUniversity of Ferrara, Ferrara, Italy.ORCID 0000-0003-3566-1362
Simonetta FalzoniUniversity of Ferrara, Ferrara, Italy.
Stefanie FenskeLudwig Maximilian University of Munich, Munich, Germany.ORCID 0000-0002-6994-8401
Anna Fortuny-GomezUniversity of East Anglia, Norwich, UK.
Samuel FountainUniversity of East Anglia, Norwich, UK.ORCID 0000-0002-6028-0548
Chandy GeorgeNanyang Technological University, Singapore, Singapore.
Steve A N GoldsteinUniversity of California Irvine, Irvine, USA.ORCID 0000-0001-5207-5061
Christian GrimmLudwig Maximilian University of Munich, Munich, Germany.
Stephan GrissmerUlm University, Ulm, Germany.
Kotdaji HaUniversity of California San Francisco, San Francisco, USA.ORCID 0000-0002-0866-0842
Verena HammelmannLudwig Maximilian University of Munich, Munich, Germany.
Israel HanukogluAriel University, Ariel, Israel.ORCID 0000-0003-3889-0320
Meiqin HuHangzhou, China.
Ad P IjzermanLeiden University, Leiden, Netherlands.ORCID 0000-0002-1182-2259
Sairam V JabbaDuke University, Durham, USA.ORCID 0000-0003-0646-3519
Mike JarvisUniversity of Illinois, Chicago, USA.
Anders A JensenUniversity of Copenhagen, Copenhagen, Denmark.ORCID 0000-0003-2366-6051
Sven E JordtDuke University, Durham, USA.ORCID 0000-0001-6171-5622
Leonard K KaczmarekYale University, New Haven, USA.ORCID 0000-0001-5128-6326
Stephan KellenbergerUniversity of Lausanne, Lausanne, Switzerland.ORCID 0000-0003-1755-6198
Charles KennedyStrathclyde University, Glasgow, UK.ORCID 0000-0001-9661-5437
Brian KingUniversity College London, London, UK.ORCID 0000-0003-1338-3234
Philip KitchenAston University, Birmingham, UK.ORCID 0000-0002-1558-4673
Qiang LiuHangzhou, China.
Joseph W LynchUniversity of Queensland, Brisbane, Australia.
Jessica MeadesUniversity of East Anglia, Norwich, UK.
Verena MehlfeldLudwig Maximilian University of Munich, Munich, Germany.
Annette NickeLudwig Maximilian University of Munich, Munich, Germany.
Stefan OffermannsMax Planck Institute for Heart and Lung Research/JW Goethe University, Bad Nauheim/Frankfurt, Germany.ORCID 0000-0001-8676-6805
Edward Perez-ReyesUniversity of Virginia, Charlottesville, USA.ORCID 0000-0001-6237-3863
Leigh D PlantNortheastern University, Boston, USA.ORCID 0000-0002-1622-1655
Lachlan RashUniversity of Queensland, St. Lucia, Australia.ORCID 0000-0003-3616-0279
Dejian RenUniversity of Pennsylvania, Philadelphia, USA.ORCID 0000-0002-6592-9457
Mootaz M SalmanUniversity of Oxford, Oxford, UK.ORCID 0000-0002-5683-1706
Werner SieghartMedical University of Vienna, Vienna, Austria.ORCID 0000-0002-0443-0302
Lucia G SivilottiUniversity College London, London, UK.
Trevor G SmartUniversity College London, London, UK.ORCID 0000-0002-9089-5375
Terrance P SnutchUniversity of British Columbia, Vancouver, Canada.ORCID 0000-0001-5182-1296
Jinbin TianUniversity of Texas at Houston, Houston, USA.ORCID 0000-0002-5516-7778
James S TrimmerUniversity of California Davis, Davis, USA.ORCID 0000-0002-6117-3912
Charlotte Van den EyndeCatholic University of Leuven, Leuven, Belgium.ORCID 0000-0003-0477-3150
Joris VriensCatholic University of Leuven, Leuven, Belgium.ORCID 0000-0002-2502-0409
Aguan D WeiUniversity of Washington, Seattle, USA.
Brenda T WinnNortheastern University, Boston, USA.
Heike WulffUniversity of California Davis, Davis, USA.ORCID 0000-0003-4437-5763
Haoxing XuUniversity of Michigan, Ann Arbor, USA.ORCID 0000-0003-3561-4654
Fan YangHangzhou, China.
Wei FangHangzhou, China.
Lixia YueUniversity of Connecticut, Farmington, USA.ORCID 0000-0002-3558-091X
Xiaoli ZhangUniversity of Michigan, Ann Arbor, USA.ORCID 0000-0002-0507-6317
Michael ZhuUniversity of Texas at Houston, Houston, USA.ORCID 0000-0002-5676-841X

Funding

Advanced TRPA1 Inhibitor for the Treatment of Chlorine Inhalation InjuryU01ES030672 · NIEHS · DUKE UNIVERSITY · PI ACHANTA, SATYANARAYANA, JORDT, SVEN-ERIC · 2019 to 2021
$2.3M
Pulmonary cell fate and lung repair in rodent and porcine models of chlorine and phosgene inhalation injuriesR01ES034387 · NIEHS · DUKE UNIVERSITY · PI ACHANTA, SATYANARAYANA, JORDT, SVEN-ERIC · 2022 to 2024
$1.4M
Medical Research Council MR/T002581/1NIEHS NIH HHS R01 ES034387NIEHS NIH HHS U01 ES030672
6 · The paper itself

Abstract

The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and over 6000 interactions with about 3900 ligands. There is an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (https://www.guidetopharmacology.org/), which provides more detailed views of target and ligand properties. Although the Concise Guide constitutes almost 500 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point-in-time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.16178. Ion channels are one of the six major pharmacological targets into which the Guide is divided, with the others being: G protein-coupled receptors, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid-2023, and supersedes data presented in the 2021/22, 2019/20, 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature and Standards Committee of the International Union of Basic and Clinical Pharmacology (NC-IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.

Indexed as

Databases, PharmaceuticalPharmacologyDatabases, FactualHumansIon ChannelsLigandsReceptors, G-Protein-CoupledIon ChannelsLigandsReceptors, G-Protein-Coupled

Identifiers

PMID38123150
PMCPMC11339754

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.