Evidence map›Paper›PMID 38117934›Full record

ArticleACS applied materials & interfaces2024

Temporal Changes in the Surface Chemistry and Topography of Reactive Ion Plasma-Treated Poly(vinyl alcohol) Alter Endothelialization Potential.

Ryan A Faase, Novella M Keeling, Justin S Plaut, Christian Leycam, Gabriela Acevedo Munares, Monica T Hinds, Joe E Baio, Patrick L Jurney

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS applied materials & interfaces, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Ryan A FaaseSchool of Chemical, Biological, and Environmental Engineering, Oregon State University, 103 Gleeson Hall, Corvallis, Oregon 97331, United States.
Novella M KeelingBiomedical Engineering Program, University of Colorado Boulder, 1111 Engineering Drive 521 UCB, Boulder, Colorado 80309-0521, United States.
Justin S PlautCancer Early Detection Advanced Research Center, Knight Cancer Institute, Oregon Health and Science University, 3303 SW Bond Ave, Portland, Oregon 97239, United States.ORCID 0000-0003-3217-9298
Christian LeycamDepartment of Biomedical Engineering, San José State University, One Washington Square, San Jose, California 95112-3613, United States.
Gabriela Acevedo MunaresDepartment of Biomedical Engineering, San José State University, One Washington Square, San Jose, California 95112-3613, United States.
Monica T HindsDepartment of Biomedical Engineering, Oregon Health and Science University, 3303 SW Bond Ave, Portland, Oregon 97239, United States.
Joe E BaioSchool of Chemical, Biological, and Environmental Engineering, Oregon State University, 103 Gleeson Hall, Corvallis, Oregon 97331, United States.
Patrick L JurneyDepartment of Biomedical Engineering, San José State University, One Washington Square, San Jose, California 95112-3613, United States.ORCID 0000-0002-4099-2927
Oregon Health & Science University · USSan Jose State University · USOregon State University · US

Funding

Contact Pathway Activation on Vascular DevicesR01HL144113 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI HINDS, MONICA T, MCCARTY, OWEN J · 2018 to 2025
$6.0M
Reactive Ion Plasma Treatment of Cardiovascular Biomaterials to Understand the Effect of Nanotopography on EndothelializationSC2GM140991 · NIGMS · SAN JOSE STATE UNIVERSITY · PI JURNEY, PATRICK · 2021 to 2023
$426k
Microfluidic Photoreactor for Treatment of HyperbilirubinemiaR21HD096301 · NICHD · OREGON STATE UNIVERSITY · PI BAIO, JOE E, HIGGINS, ADAM Z · 2018 to 2019
$372k
NHLBI NIH HHS R01 HL144113NICHD NIH HHS R21 HD096301NIGMS NIH HHS SC2 GM140991
6 · The paper itself

Abstract

Synthetic small-diameter vascular grafts (<6 mm) are used in the treatment of cardiovascular diseases, including coronary artery disease, but fail much more readily than similar grafts made from autologous vascular tissue. A promising approach to improve the patency rates of synthetic vascular grafts is to promote the adhesion of endothelial cells to the luminal surface of the graft. In this study, we characterized the surface chemical and topographic changes imparted on poly(vinyl alcohol) (PVA), an emerging hydrogel vascular graft material, after exposure to various reactive ion plasma (RIP) surface treatments, how these changes dissipate after storage in a sealed environment at standard temperature and pressure, and the effect of these changes on the adhesion of endothelial colony-forming cells (ECFCs). We showed that RIP treatments including O

Indexed as

Endothelial CellsVascular GraftingBlood Vessel ProsthesisEthanolPlasmaPolyvinyl AlcoholEthanolPolyvinyl Alcoholcardiovascular biomaterialsendothelializationhydrophobic recoverynanotopographypoly(vinyl alcohol)reactive ion plasma

Identifiers

PMID38117934
PMCPMC10788828
OpenAlexW4390036783

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.