Evidence map›Paper›PMID 38117587›Full record

ArticleGut microbes

Precocious infant fecal microbiome promotes enterocyte barrier dysfuction, altered neuroendocrine signaling and associates with increased childhood obesity risk.

Germaine J M Yong, Cara E Porsche, Alexandra R Sitarik, Kei E Fujimura, Kathryn McCauley, Dat T Nguyen, Albert M Levin, Kimberley J Woodcroft, Dennis R Ownby, Andrew G Rundle and 3 more

Open access · goldAbstract read
In one paragraph

Article in Gut microbes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 1 country.

Germaine J M YongDivision of Gastroenterology, Department of Medicine, University of California, San Francisco, CA, USA.
Cara E PorscheDivision of Gastroenterology, Department of Medicine, University of California, San Francisco, CA, USA.
Alexandra R SitarikDepartment of Public Health Sciences, Henry Ford Health System, Detroit, MI, USA.
Kei E FujimuraDivision of Gastroenterology, Department of Medicine, University of California, San Francisco, CA, USA.
Kathryn McCauleyDivision of Gastroenterology, Department of Medicine, University of California, San Francisco, CA, USA.
Dat T NguyenDivision of Gastroenterology, Department of Medicine, University of California, San Francisco, CA, USA.
Albert M LevinDepartment of Public Health Sciences, Henry Ford Health System, Detroit, MI, USA.
Kimberley J WoodcroftDepartment of Public Health Sciences, Henry Ford Health System, Detroit, MI, USA.
Dennis R OwnbyDivision of Allergy and Clinical Immunology, Department of Pediatrics, Augusta University, Augusta, GA, USA.
Andrew G RundleDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA.
Christine C JohnsonDepartment of Public Health Sciences, Henry Ford Health System, Detroit, MI, USA.
Andrea Cassidy-BushrowDepartment of Public Health Sciences, Henry Ford Health System, Detroit, MI, USA.
Susan V LynchDivision of Gastroenterology, Department of Medicine, University of California, San Francisco, CA, USA.ORCID 0000-0001-5695-7336
Henry Ford Health System · USUniversity of California, San Francisco · USAugusta University · USCalifornia Department of Public Health · USColumbia University · USJohns Hopkins University · US

Funding

The Effect of Dog-Keeping and the Intestinal Microbiota on Immune DevelopmentP01AI089473 · NIAID · HENRY FORD HEALTH SYSTEM · PI OWNBY, DENNIS R · 2012 to 2024
$25.7M
UCSF Nutrition Obesity Research CenterP30DK098722 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHRISTIAN VAISSE · 2015 to 2026
$14.6M
RESEARCH CORE-- SIGNAL TRANSDUCTIONP30ES006639 · NIEHS · WAYNE STATE UNIVERSITY · PI DERESKI, MARY O · 1994 to 2008
$13.1M
New York Regional Center for Diabetes Translation Research - Translational Intervention Methodology CoreP30DK111022 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI JEFFREY GONZALEZ · 2016 to 2026
$7.8M
Delivery mode, environment and the gut microbiome: influence on childhood body sizeR01HD082147 · NICHD · HENRY FORD HEALTH SYSTEM · PI CASSIDY-BUSHROW, ANDREA E · 2016 to 2020
$3.0M
Early Environmental Hygiene and Pediatric AtopyR01AI050681 · NIAID · HENRY FORD HEALTH SYSTEM · PI JOHNSON, CHRISTINE C · 2002 to 2006
$2.9M
Epidemiology of multimorbid pediatric atopic and airway diseases and the impact of prenatal maternal environmental exposures and placental epigeneticsUG3OD035518 · OD · HENRY FORD HEALTH SYSTEM · PI EAPEN, AMY, JOHNSON, CHRISTINE C · 2023 to 2024
$1.7M
NIAID NIH HHS P01 AI089473NIAID NIH HHS R01 AI050681NICHD NIH HHS R01 HD082147NIDDK NIH HHS P30 DK098722NIDDK NIH HHS P30 DK111022NIEHS NIH HHS P30 ES006639NIH HHS UG3 OD035518
6 · The paper itself

Abstract

Early life gut microbiome composition has been correlated with childhood obesity, though microbial functional contributions to disease origins remain unclear. Here, using an infant birth cohort (

Indexed as

Gastrointestinal MicrobiomeMicrobiotaPediatric ObesityChildEnterocytesFecesHumansInfantchildhood obesityEarly lifegut barrier dysfunctiongut microbiomenutrition

Identifiers

PMID38117587
PMCPMC10761186
OpenAlexW4390014114

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.