Evidence map›Paper›PMID 38117405›Full record

ReviewDrug delivery and translational research2024

Cell-derived biomimetic nanoparticles for the targeted therapy of ALI/ARDS.

Rui Gao, Peihong Lin, Zhengyu Fang, Wenjing Yang, Wenyan Gao, Fangqian Wang, Xuwang Pan, Wenying Yu

Abstract readReview
PubMed Publisher
In one paragraph

Review in Drug delivery and translational research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Nutrients · 2026
    Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Rui Gao *School of Pharmacy, Hangzhou Medical College, Hangzhou, 310013, China.
Peihong Lin *School of Pharmacy, Hangzhou Medical College, Hangzhou, 310013, China.
Zhengyu Fang *School of Pharmacy, Hangzhou Medical College, Hangzhou, 310013, China.
Wenjing YangSchool of Pharmacy, Hangzhou Medical College, Hangzhou, 310013, China.
Wenyan GaoSchool of Pharmacy, Hangzhou Medical College, Hangzhou, 310013, China.
Fangqian WangSchool of Pharmacy, Hangzhou Medical College, Hangzhou, 310013, China.
Xuwang PanDepartment of Pharmaceutical Preparation, Affiliated Hangzhou Xixi Hospital, Zhejiang University School of Medicine, Hangzhou, 310013, China. pxuwang@163.com.
Wenying YuSchool of Pharmacy, Hangzhou Medical College, Hangzhou, 310013, China. wenyingyu@hmc.edu.cn.ORCID 0000-0003-3168-9472

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are common clinical critical diseases with high morbidity and mortality. Especially since the COVID-19 outbreak, the mortality rates of critically ill patients with ARDS can be as high as 60%. Therefore, this problem has become a matter of concern to respiratory critical care. To date, the main clinical measures for ALI/ARDS are mechanical ventilation and drug therapy. Although ventilation treatment reduces mortality, it increases the risk of hyperxemia, and drug treatment lacks safe and effective delivery methods. Therefore, novel therapeutic strategies for ALI/ARDS are urgently needed. Developments in nanotechnology have allowed the construction of a safe, efficient, precise, and controllable drug delivery system. However, problems still encounter in the treatment of ALI/ARDS, such as the toxicity, poor targeting ability, and immunogenicity of nanomaterials. Cell-derived biomimetic nanodelivery drug systems have the advantages of low toxicity, long circulation, high targeting, and high bioavailability and show great therapeutic promises for ALI/ARDS owing to their acquired cellular biological features and some functions. This paper reviews ALI/ARDS treatments based on cell membrane biomimetic technology and extracellular vesicle biomimetic technology, aiming to achieve a significant breakthrough in ALI/ARDS treatments.

Indexed as

Acute Lung InjuryNanoparticlesRespiratory Distress SyndromeAnimalsBiomimetic MaterialsBiomimeticsCOVID-19COVID-19 Drug TreatmentDrug Delivery SystemsHumansALI/ARDSBiomimetic nanotechnologyCell membraneExtracellular vesicleTargeted delivery

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.