Evidence map›Paper›PMID 38117324›Full record

ArticleAnalytical and bioanalytical chemistry2024

MNAzyme catalyzed signal amplification-mediated lateral flow biosensor for portable and sensitive detection of mycotoxin in food samples.

Yan Yang, Yiheng Shi, Xianlong Zhang, Guoliang Li

Abstract read
PubMed Publisher
In one paragraph

Article in Analytical and bioanalytical chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Yan YangSchool of Biological and Pharmaceutical Engineering, Lanzhou Jiao Tong University, Lanzhou, 730070, China.
Yiheng ShiSchool of Food and Biological Engineering, Shaanxi University of Science and Technology, Xi'an, 710021, China.
Xianlong ZhangSchool of Food and Biological Engineering, Shaanxi University of Science and Technology, Xi'an, 710021, China.
Guoliang LiSchool of Food and Biological Engineering, Shaanxi University of Science and Technology, Xi'an, 710021, China. 61254368@163.com.
Shaanxi University of Science and Technology · CNLanzhou Jiaotong University · CN

Funding

National Natural Science Foundation of China 22076115National Natural Science Foundation of China 32022069
6 · The paper itself

Abstract

Here, an enzyme-free lateral flow aptasensor was designed by target-induced strand-displacement effect and followed by the activation of multi-component nucleic acid enzyme (MNAzyme)-mediated cleavage to enable rapid and portable ochratoxin A (OTA) detection. The substrate was prepared as an oligonucleotide strand modified with magnetic beads (MB) and human chorionic gonadotropin (hCG). The interaction of OTA with the aptamer induces the release of blocking DNA, which hybridized with three separated subunits of DNA, forming a sequence-specific MNAzyme catalytic core. This core subsequently initiated an enzyme-free MNAzyme cleavage reaction in the presence of the Mg

Indexed as

Aptamers, NucleotideBiosensing TechniquesMycotoxinsOchratoxinsCatalysisDNADNA ProbesHumansLimit of DetectionAptamers, NucleotideDNADNA ProbesMycotoxinsOchratoxinsEnzyme-freeFood sampleMNAzymeMycotoxinPortablePregnancy test strip

Identifiers

PMID38117324
OpenAlexW4389992886

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.