Evidence map›Paper›PMID 38116916›Full record

Trial reportAlzheimer's & dementia : the journal of the Alzheimer's Association2024

Impact of the iWHELD digital person-centered care program on quality of life, agitation and psychotropic medications in people with dementia living in nursing homes during the COVID-19 pandemic: A randomized controlled trial.

Joanne McDermid, William Henley, Anne Corbett, Gareth Williams, Jane Fossey, Linda Clare, Chris Fox, Dag Aarsland, Zunera Khan, Maria Soto and 8 more

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 6 institutions in 3 countries.

Joanne McDermidUniversity of Exeter Medical School, University of Exeter, Exeter, UK.
William HenleyUniversity of Exeter Medical School, University of Exeter, Exeter, UK.
Anne CorbettUniversity of Exeter Medical School, University of Exeter, Exeter, UK.ORCID 0000-0003-2015-0316
Gareth WilliamsInstitute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Jane FosseyUniversity of Exeter Medical School, University of Exeter, Exeter, UK.
Linda ClareUniversity of Exeter Medical School, University of Exeter, Exeter, UK.
Chris FoxUniversity of Exeter Medical School, University of Exeter, Exeter, UK.
Dag AarslandInstitute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Zunera KhanInstitute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Maria SotoResearch and Clinical Alzheimer's Disease Center, CMRR Gérontopôle, CHU Toulouse, AGING team, axe MAINTAIN CERPOP, Toulouse, France.
Barbara Woodward-CarltonAlzheimer's Society UK, London, UK.
Esme Moniz CookFaculty of Health Sciences, University of Hull, Hull, UK.
Jeffrey CummingsChambers-Grundy Center for Transformative Neuroscience, Department of Brain Health, School of Integrated Health Sciences, University of Nevada Las Vegas (UNLV), Las Vegas, Nevada, USA.
Adrienne SweetnamUniversity of Exeter Medical School, University of Exeter, Exeter, UK.
Xavier ChanUniversity of Exeter Medical School, University of Exeter, Exeter, UK.
Megan LawrenceUniversity of Exeter Medical School, University of Exeter, Exeter, UK.
Clive BallardUniversity of Exeter Medical School, University of Exeter, Exeter, UK.
iWHELD study group
University of Exeter · GBKing's College London · GBAlzheimer's Society · GBMédipole Garonne · FRUniversity of Hull · GBUniversity of Nevada, Las Vegas · US

Funding

Trial-Ready Cohort for Preclinical/Prodromal Alzheimer's DiseaseR01AG053798 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI AISEN, PAUL S., CUMMINGS, JEFFREY L. · 2017 to 2022
$39.4M
Renewal of Centers of Biomedical Research Excellence (COBRE) (Phase 2) CNTN - ResubmissionP20GM109025 · NIGMS · CLEVELAND CLINIC FOUNDATION · PI Robert J. Fox, Jefferson Kinney · 2015 to 2026
$22.8M
NVEDARC Clinical CoreP20AG068053 · NIA · CLEVELAND CLINIC FOUNDATION · PI WINT, DYLAN · 2020 to 2022
$3.3M
Alzheimer's Clinical Trial InnOvatioN (ACTION) InitiativeR35AG071476 · NIA · UNIVERSITY OF NEVADA LAS VEGAS · PI CUMMINGS, JEFFREY L. · 2021 to 2025
$2.9M
Medical Research Council MR/V027794/1NIA NIH HHS P20 AG068053NIA NIH HHS R35 AG071476NIGMS NIH HHS P20 GM109025
6 · The paper itself

Abstract

introductioniWHELD is a digital person-centered care program for people with dementia in nursing homes adapted for remote delivery during the COVID-19 pandemic.

methodsA 16-week two-arm cluster-randomized controlled trial in 149 UK nursing homes compared iWHELD with treatment as usual (TAU). Primary outcome was the overall quality of life with secondary outcomes of agitation and psychotropic use.

resultsiWHELD conferred benefit to quality of life on the primary (F = 4.3, p = 0.04) and secondary measures of quality of life (F = 6.45, p = 0.01) and reduced psychotropic medication use (χ DISCUSSION: iWHELD confers benefits to quality of life and key measures of well-being, can be delivered during the challenging conditions of a pandemic, and should be considered for use alongside any emerging pharmacological treatment for neuropsychiatric symptoms. HIGHLIGHTS: iWHELD is the only remote, digital delivery nursing home training programme for dementia care iWHELD improved quality of life in people with dementia and reduced antipsychotic use without worsening of agitation Residents who contracted Covid-19 during the study also experienced benefits from iWHELD iWHELD offers a valuable, pandemic-safe tool for improving dementia care.

Indexed as

COVID-19DementiaAgedHomes for the AgedHumansNursing HomesPandemicsPatient-Centered CarePsychomotor AgitationQuality of LifeagitationCOVID-19dementiadigitaliWHELDnursing homeperson-centered carepsychotropicquality of life

Identifiers

PMID38116916
PMCPMC10984502
OpenAlexW4390002451

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.