Evidence map›Paper›PMID 38116566›Full record

ArticleIranian journal of pharmaceutical research : IJPR

Evaluation of Antioxidant and Antibacterial Effects of Lyophilized Cell-Free Probiotic Supernatants of Three

Maryam Torshabi, Mohammad Mahdi Bardouni, Atieh Hashemi

Open access · hybridAbstract read
In one paragraph

Article in Iranian journal of pharmaceutical research : IJPR. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Anti-Persisters Activity ofInternational journal of molecular sciences · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Maryam TorshabiDepartment of Dental Biomaterials, School of Dentistry, Shahid Beheshti University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0003-4827-0942
Mohammad Mahdi BardouniDepartment of Pharmaceutical Biotechnology, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0009-0008-9882-5663
Atieh HashemiDepartment of Pharmaceutical Biotechnology, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0001-7121-5306
Shahid Beheshti University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Periodontitis is a chronic disease characterized by the inflammation of the periodontium and leads to progressive damage, such as gingival atrophy, alveolar bone loss, and tooth loss. Objectives: This study aimed to evaluate the antioxidant activity and antimicrobial effects of lyophilized cell-free supernatants (LCFSs) derived from three probiotic strains of Methods: The antibacterial effects of LCFSs of three probiotic bacteria were investigated by determining the minimum inhibitory concentration and minimum bactericidal concentration. Then, the effect of LCFSs on the survival and migration of PDLSCs was investigated by the MTT method (at 24 and 72 hours) and scratch test (at 0, 24, and 48 hours), respectively. Finally, the antioxidant effect of LCFSs was assessed by the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay and ferric reducing/antioxidant power methods. Results: The antibacterial properties of different concentrations of acidic and neutral LCFSs derived from three studied probiotic bacteria on Conclusions: The results revealed that 5% (v/v) 48-hour acidic and neutral supernatants of three studied probiotics might play a beneficial role in controlling periodontitis.

Indexed as

Antioxidant ActivityCytotoxicityPeriodontal LigamentPeriodontitisProbiotics

Identifiers

PMID38116566
PMCPMC10728833
OpenAlexW4383875218

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.