ArticleOne health (Amsterdam, Netherlands)2023
The role of vaccination and environmental factors on outbreaks of high pathogenicity avian influenza H5N1 in Bangladesh.
Article in One health (Amsterdam, Netherlands), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- A phylogeny-informed mathematical modeling of HPAI H5N1 transmission dynamics and effectiveness of control measures.One health (Amsterdam, Netherlands) · 2026Article
- Evaluating transient risk factors for avian influenza outbreaks in Canada using case-crossover study and machine learning.Poultry science · 2026Article
- Integrated region-specific modeling of H5 avian influenza in Asia using ENSO-based forecasts.One health (Amsterdam, Netherlands) · 2026Article
- Avian influenza and One Health: bridging animal and human health through integrated surveillance and vaccination.Frontiers in cellular and infection microbiology · 2026Review
- Projecting the impacts of climate and land-use change on avian influenza suitability in Bangladesh.One health (Amsterdam, Netherlands) · 2025Article
- Epidemiology and evolutionary dynamics of H9N2 avian influenza virus in Bangladesh.Emerging microbes & infections · 2025Article
- Can public-domain datasets be leveraged to identify factors associated with the occurrence of African swine fever in europe?Acta veterinaria Scandinavica · 2025Article
- Article
- India's public health risk from the emerging zoonotic bird flu (H5N1) transmission from backyard flock: a call for people-centric actions for improved sustainable development goals.Tropical animal health and production · 2025Review
- Detection and prevalence of avian influenza epidemic in the southwest of Poyang Lake and analysis of the influence of meteorological factors.One health (Amsterdam, Netherlands) · 2025Article
- - Invited Review - Challenges and constraints to the sustainability of poultry farming in Republic of Korea.Animal bioscience · 2025Article
- Association of poultry vaccination with interspecies transmission and molecular evolution of H5 subtype avian influenza virus.Science advances · 2025Article
- Investigating the role of environmental factors in the French highly pathogenic avian influenza epizootic in 2022-2023.Frontiers in veterinary science · 2025Article
- Phylodynamics of high pathogenicity avian influenza virus in Bangladesh identifying domestic ducks as the amplifying host reservoir.Emerging microbes & infections · 2024Article
- Artificial intelligence-based prediction of pathogen emergence and evolution in the world of synthetic biology.Microbial biotechnology · 2024Review
- Therapeutic Potential ofInternational journal of molecular sciences · 2024Article
- Re-evaluating efficacy of vaccines against highly pathogenic avian influenza virus in poultry: A systematic review and meta-analysis.One health (Amsterdam, Netherlands) · 2024Article
- Avian 'Bird' Flu - undue media panic or genuine concern for pandemic potential requiring global preparedness action?IJID regions · 2024Article
- Farm biosecurity practices affecting avian influenza virus circulation in commercial chicken farms in Bangladesh.One health (Amsterdam, Netherlands) · 2024Article
- Identification of Blastocystis spp. in Urban Rodents of Different Districts in Southwestern Iran: Subtype Distribution and Possible Zoonotic Potential.Acta parasitologica · 2024Article
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5 authors.
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Abstract
High Pathogenicity Avian Influenza (HPAI) H5N1 outbreaks continue to wreak havoc on the global poultry industry and threaten the health of wild bird populations, with sporadic spillover in humans and other mammals, resulting in widespread calls to vaccinate poultry. Bangladesh has been vaccinating poultry since 2012, presenting a prime opportunity to study the effects of vaccination on HPAI H5N1circulation in both poultry and wild birds. We investigated the efficacy of vaccinating commercial poultry against HPAI H5N1 along with climatic and socio-economic factors considered potential drivers of HPAI H5N1 outbreak risk in Bangladesh. Using a multivariate modeling approach, we estimated that the rate of outbreaks was 18 times higher before compared to after vaccination, with winter months having a three times higher chance of outbreaks than summer months. Variables resulting in small but significant increases in outbreak rate were relatively low ambient temperatures for the time of year, literacy rate, chicken and duck density, crop density, and presence of highways; this may be attributable to low temperatures supporting viral survival outside the host, higher literacy driving reporting rate, density of the host reservoir, and spread of the virus through increased connectivity. Despite the substantial impact of vaccination on outbreaks, we note that HPAI H5N1 is still enzootic in Bangladesh; vaccinated poultry flocks have high rates of H5N1 prevalence, and spillover to wild birds has increased. Vaccination in Bangladesh thus bears the risk of supporting "silent spread," where the vaccine only provides protection against disease and not also infection. Our findings underscore that poultry vaccination can be part of holistic HPAI mitigation strategies when accompanied by monitoring to avoid silent spread.
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