Evidence map›Paper›PMID 38116430›Full record

ArticleACS medicinal chemistry letters2023

Characterization of 2,4-Dianilinopyrimidines Against Five

Han Wee Ong, Chandi de Silva, Krisha Avalani, Frank Kwarcinski, Christopher R Mansfield, Michael Chirgwin, Anna Truong, Emily R Derbyshire, Reena Zutshi, David H Drewry

Open access · hybridAbstract read
In one paragraph

Article in ACS medicinal chemistry letters, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Covalent inhibition ofiScience · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Han Wee OngStructural Genomics Consortium and Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.ORCID https://orcid.org/0000-0003-3232-2373
Chandi de SilvaLuceome Biotechnologies, LLC, 1665 East 18th Street, Suite 106, Tucson, Arizona 85719, United States.
Krisha AvalaniLuceome Biotechnologies, LLC, 1665 East 18th Street, Suite 106, Tucson, Arizona 85719, United States.
Frank KwarcinskiLuceome Biotechnologies, LLC, 1665 East 18th Street, Suite 106, Tucson, Arizona 85719, United States.
Christopher R MansfieldDepartment of Molecular Genetics and Microbiology, Duke University Medical Center, 213 Research Drive, Durham, North Carolina 27710, United States.
Michael ChirgwinDepartment of Chemistry, Duke University, 124 Science Drive, Durham, North Carolina 27708, United States.
Anna TruongDepartment of Chemistry, Duke University, 124 Science Drive, Durham, North Carolina 27708, United States.
Emily R DerbyshireDepartment of Molecular Genetics and Microbiology, Duke University Medical Center, 213 Research Drive, Durham, North Carolina 27710, United States.ORCID https://orcid.org/0000-0001-6664-8844
Reena ZutshiLuceome Biotechnologies, LLC, 1665 East 18th Street, Suite 106, Tucson, Arizona 85719, United States.
David H DrewryStructural Genomics Consortium and Division of Chemical Biology and Medicinal Chemistry, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, United States.ORCID https://orcid.org/0000-0001-5973-5798
Duke University · USLuceome Biotechnologies (United States) · USUniversity of North Carolina at Chapel Hill · US

Funding

Kinase Targeted Antimalarial AgentsR44AI150237 · NIAID · LUCEOME BIOTECHNOLOGIES, LLC · PI ZUTSHI, REENA · 2020 to 2021
$1.8M
NIAID NIH HHS R44 AI150237
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID38116430
PMCPMC10726455
OpenAlexW4389043310

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.