ArticlePreventive medicine reports2023
Analysis of the global burden of disease study highlights the global, regional, and national trends of idiopathic epilepsy epidemiology from 1990 to 2019.
Article in Preventive medicine reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 39 citations in OpenAlex.
- Community perspectives and recommendations to reduce epilepsy stigma and enhance effective management of epilepsy in Uganda: A qualitative study.Epilepsy & behavior : E&B · 2026Article
- Neuroinflammation promotes the development of pharmacoresistant epilepsy by triggering the MSK1/CREB signaling pathway.Scientific reports · 2026Article
- A pilot comparative study of intraoperative results and surgical outcomes between asleep-awake-asleep and general anesthesia modalities in temporal lobe resections.Neurosurgical review · 2026Article
- Epidemiological Trends of Idiopathic Epilepsy in Asia: 1990-2021 - An Analysis from the Global Burden of Disease Study 2021.Neuroepidemiology · 2026Article
- Global temporal trends and projections of epilepsy in women of childbearing age: insights from the global burden of disease study 2021.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Article
- Trends and projections of ischemic heart disease burden in the Belt and Road countries and China from 1990 to 2021: a study based on the 2021 global burden of disease.Annals of medicine · 2025Article
- Global, regional, and national children and adolescent epilepsy burden, 1990-2021: an analysis based on the global burden of disease study 2021.Annals of medicine · 2025Article
- Global burden trends of idiopathic epilepsy in young adults from 1990 to 2035: based on the global burden of disease study 2021.BMC neurology · 2025Article
- Epidemiological Study of Childhood Idiopathic Epilepsy from 1990 to 2021 at Global, Regional, and National Scales.Mayo Clinic proceedings. Innovations, quality & outcomes · 2025Article
- Global, regional, and national burden of idiopathic epilepsy in older adults, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021.BMC medicine · 2025Article
- Global, regional, and national burden of epilepsy, 1990-2021: a systematic analysis for the Global Burden of Disease Study in 2021.Cost effectiveness and resource allocation : C/E · 2025Article
- Global, regional, and national burden of epilepsy, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021.The Lancet. Public health · 2025Article
- Global, regional, and national epilepsy of unknown cause incidence and mortality, 1990-2036: cross-national health inequalities and predictive analytics.Frontiers in neurology · 2025Article
- The global, regional, and national prostate cancer burden and trends from 1990 to 2021, results from the global burden of disease study 2021.Frontiers in public health · 2025Article
- Evolving trends and burden of idiopathic epilepsy among children (0-14 years), 1990-2021: a systematic analysis for the Global Burden of Disease study 2021.Frontiers in neurology · 2025Article
- Anterior temporal lobectomy and selective AmygdaloHippocampectomy complications across Europe: review, meta-analysis, and Delphi consensus.Brain & spine · 2025Review
- Trends and predictive research on the global burden of ischemic heart disease from 1990 to 2021: an analysis of the Global Burden of Disease study 2021.Frontiers in public health · 2025Article
- Current Role of Brivaracetam in the Management of Epilepsy in Adults and Children: A Systematic Review.Cureus · 2024Review
- Trigonelline as an anticonvulsant agent: mechanistic insights into NMDA receptor expression and oxidative stress balance.Scientific reports · 2024Article
- Systematic Review of Explainable Artificial Intelligence for Epileptic Seizure Onset Early Warning: Towards Responsible Artificial Intelligence.Healthcare technology lettersReview
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Epilepsy is a profound disorder, accounting for roughly 1% of the global disease burden. It can result in premature death and significant disability. To comprehensively understand the current dynamics and trends of idiopathic epilepsy, a deep insight into its epidemiological attributes is vital. We evaluated the incidence, prevalence, mortality, and disability-adjusted life years associated with idiopathic epilepsy from 1990 to 2019 using data and methodologies from the Global Burden of Disease Study. In 2019, there were approximately 2,898,222 individuals diagnosed with idiopathic epilepsy. Intriguingly, from 1990 to 2019, the age-standardized incidence rate of idiopathic epilepsy was consistently lower in women compared to men. Over these three decades, global mortality connected to idiopathic epilepsy increased by 13.95%. However, within the same period, age-standardized death rates for idiopathic epilepsy decreased from 1.94 per 100,000 population to 1.46 per 100,000 population. Predictions indicate an increase in the incidence of idiopathic epilepsy across all age brackets through 2035, especially among the elderly aged 80 and above. Mortality rates are projected to climb for those aged 80 and above while remaining relatively unchanged in other age demographics. Idiopathic epilepsy continues to be a significant contributor to both disability and death. The findings of our study underscore the critical importance of incorporating idiopathic epilepsy management into modern healthcare frameworks. Such strategic inclusion can enhance public awareness of relevant risk factors and the range of available therapeutic interventions.
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