Evidence map›Paper›PMID 38116063›Full record

ArticleMedComm2023

Identification of RP11-770J1.4 as immune-related lncRNA regulating the CTXN1-cGAS-STING axis in histologically lower-grade glioma.

Qiyuan Zhuang, Chaxian Liu, Yihan Hu, Ying Liu, Yingying Lyu, Yuheng Liao, Liang Chen, Hui Yang, Ying Mao

Open access · goldAbstract read
In one paragraph

Article in MedComm, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Qiyuan ZhuangDepartment of Neurosurgery Huashan Hospital, Fudan University Shanghai China.
Chaxian LiuDepartment of Neurosurgery Huashan Hospital, Fudan University Shanghai China.
Yihan HuSchool of Life Sciences, Fudan University Shanghai China.
Ying LiuDepartment of Pathology School of Basic Medical Sciences, Fudan University Shanghai China.ORCID https://orcid.org/0000-0003-1662-9228
Yingying LyuDepartment of Neurosurgery Huashan Hospital, Fudan University Shanghai China.
Yuheng LiaoKey Laboratory of Medical Epigenetics and Metabolism and Molecular and Cell Biology Lab Institute of Biomedical Sciences, Shanghai Medical College, Fudan University Shanghai China.
Liang ChenDepartment of Neurosurgery Huashan Hospital, Fudan University Shanghai China.
Hui YangDepartment of Neurosurgery Huashan Hospital, Fudan University Shanghai China.
Ying MaoDepartment of Neurosurgery Huashan Hospital, Fudan University Shanghai China.
Fudan University · CNShanghai Medical College of Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human gliomas are lethal brain cancers. Emerging evidence revealed the regulatory role of long noncoding RNAs (lncRNAs) in tumors. Here, we performed a comprehensive analysis of the expression profiles of RNAs in histologically lower-grade glioma (LGG). Enrichment analysis revealed that glioma is influenced by immune-related signatures. Survival analysis further established the close correlation between network features and glioma prognosis. Subsequent experiments showed lncRNA RP11-770J1.4 regulates

Indexed as

ceRNA networkcytosolic DNA sensing pathwayimmune‐related lncRNAlower‐grade gliomasingle‐cell RNA sequencing

Identifiers

PMID38116063
PMCPMC10728758
OpenAlexW4389955765

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.