Evidence map›Paper›PMID 38115873›Full record

ArticleActa ortopedica brasileira2023

MESENCHYMAL CELLS IN ROTATOR CUFF REPAIR - TECHNIQUE DESCRIPTION AND CASE REPORTS.

Eduardo Angeli Malavolta, Vinicius Lamboglia Miceli, Jorge Henrique Assunção, Fernando Brandao Andrade-Silva, Mauro Emilio Conforto Gracitelli, Nelson Hidekazu Tatsui, Luiz César Espirandelli, Arnaldo Amado Ferreira

Abstract read
In one paragraph

Article in Acta ortopedica brasileira, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Eduardo Angeli MalavoltaUniversidade de Sao Paulo, Faculdade de Medicina, Hospital das Clinicas HC-FMUSP, São Paulo, SP, Brazil.ORCID 0000-0003-1956-6445
Vinicius Lamboglia MiceliUniversidade de Sao Paulo, Faculdade de Medicina, Hospital das Clinicas HC-FMUSP, São Paulo, SP, Brazil.ORCID 0000-0003-1752-1809
Jorge Henrique AssunçãoUniversidade de Sao Paulo, Faculdade de Medicina, Hospital das Clinicas HC-FMUSP, São Paulo, SP, Brazil.ORCID 0000-0002-2566-3471
Fernando Brandao Andrade-SilvaUniversidade de Sao Paulo, Faculdade de Medicina, Hospital das Clinicas HC-FMUSP, São Paulo, SP, Brazil.ORCID 0000-0003-3025-1719
Mauro Emilio Conforto GracitelliUniversidade de Sao Paulo, Faculdade de Medicina, Hospital das Clinicas HC-FMUSP, São Paulo, SP, Brazil.ORCID 0000-0002-0214-9576
Nelson Hidekazu TatsuiUniversidade de Sao Paulo, Faculdade de Medicina, Hospital das Clinicas HC-FMUSP, São Paulo, SP, Brazil.ORCID 0000-0002-1244-8967
Luiz César EspirandelliCriogenesis Biotecnologia Ltda, São Paulo, SP, Brazil.ORCID 0000-0001-6846-1004
Arnaldo Amado FerreiraUniversidade de Sao Paulo, Faculdade de Medicina, Hospital das Clinicas HC-FMUSP, São Paulo, SP, Brazil.ORCID 0000-0001-5097-9542

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To describe a protocol of obtention of mesenchymal stem cells and to report their use as a biological adjuvant in three patients undergoing arthroscopic rotator cuff repair. Methods: Case series of patients who underwent arthroscopic repair of isolated full-thickness supraspinatus tear using mesenchymal stem cells obtained from the bone marrow as a biological adjuvant. All patients were operated on at the same institution, by a surgeon with 13 years of experience. The cells were applied at the end of the procedure, at the tendon-bone interface, at an approximate concentration of 2,000,000 mesenchymal cells/mm Results: All patients improved with the procedure, with one excellent and two good results. All cases overcame the minimally important clinical difference. All cases reached tendon healing, without partial or complete re-tears. We observed no complications. Conclusion: Arthroscopic rotator cuff repair with added mesenchymal cells obtained from bone marrow and submitted to a cell expansion process led to good functional results and healing in all cases in the sample, with no complications.

Indexed as

ArthroscopyMesenchymal Stem Cell TransplantationRotator Cuff

Identifiers

PMID38115873
PMCPMC10726706

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.