Evidence map›Paper›PMID 38115864›Full record

ArticleMetabolism open2023

Plasma undercarboxylated osteocalcin dynamics with glycemic stress reflects insulin sensitivity and beta-cell function in humans with and without T2DM.

Kelly N Z Fuller, Erin M Bohne, Jacob T Mey, Brian K Blackburn, Victoria R Miranda, Krista A Varady, Kirstie K Danielson, Jacob M Haus

Open access · goldAbstract read
In one paragraph

Article in Metabolism open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Kelly N Z FullerDepartment of Pediatrics, Section of Endocrinology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Erin M BohneDepartment of Kinesiology and Nutrition, University of Illinois at Chicago, IL, USA.
Jacob T MeyPennington Biomedical Research Center, Louisiana State University, Baton Rouge, LA, USA.
Brian K BlackburnApplied Health Sciences and Kinesiology, Humboldt State University, Arcata, CA, USA.
Victoria R MirandaSchool of Kinesiology, University of Michigan, Ann Arbor, MI, USA.
Krista A VaradyDepartment of Kinesiology and Nutrition, University of Illinois at Chicago, IL, USA.
Kirstie K DanielsonDivision of Endocrinology and Metabolism, University of Illinois at Chicago, IL, USA.
Jacob M HausSchool of Kinesiology, University of Michigan, Ann Arbor, MI, USA.
University of Illinois Chicago · USUniversity of Michigan · USCal Poly Humboldt · USPennington Biomedical Research Center · USUniversity of Colorado Anschutz Medical Campus · US

Funding

Strategies and Functional Outcomes of Enhancing in Vivo Production of Soluble Rage IsoformsR01DK109948 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HAUS, JACOB M · 2016 to 2020
$3.1M
NIDDK NIH HHS R01 DK109948
6 · The paper itself

Abstract

This study aimed to better understand the relationship between bone-related biomarkers and nutrient stress in the context of metabolic health. We investigated plasma osteocalcin (OC) during an oral glucose challenge and experimental hyperinsulinemia in Type 2 diabetes (T2DM) and lean healthy controls (LHC). Older individuals with obesity and T2DM (n = 9) and young LHCs (n = 9) underwent a 75g oral glucose tolerance test (OGTT) and a 40 mU/m

Indexed as

AdipokinesAlkaline phosphataseBoneHyperinsulinemia-euglycemic clampOGTT

Identifiers

PMID38115864
PMCPMC10728569
OpenAlexW4389264546

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.