Evidence map›Paper›PMID 38115133›Full record

ArticleJournal of cachexia, sarcopenia and muscle2024

Validity of the diagnostic criteria from the Asian Working Group for Cachexia in advanced cancer.

Tatsuma Sakaguchi, Keisuke Maeda, Tomoko Takeuchi, Ai Mizuno, Ryoko Kato, Yuria Ishida, Junko Ueshima, Akio Shimizu, Koji Amano, Naoharu Mori

Open access · goldAbstract read
In one paragraph

Article in Journal of cachexia, sarcopenia and muscle, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Tatsuma SakaguchiPalliative Care Center, Aichi Medical University, Nagakute, Aichi, Japan.ORCID 0000-0002-2246-9526
Keisuke MaedaNutrition Therapy Support Center, Aichi Medical University Hospital, Nagakute, Aichi, Japan.
Tomoko TakeuchiDepartment of Nutrition, Aichi Medical University Hospital, Nagakute, Aichi, Japan.
Ai MizunoDepartment of Nutrition, Aichi Medical University Hospital, Nagakute, Aichi, Japan.
Ryoko KatoDepartment of Palliative and Supportive Medicine, Graduate School of Medicine, Aichi Medical University, Nagakute, Aichi, Japan.
Yuria IshidaDepartment of Palliative and Supportive Medicine, Graduate School of Medicine, Aichi Medical University, Nagakute, Aichi, Japan.
Junko UeshimaDepartment of Palliative and Supportive Medicine, Graduate School of Medicine, Aichi Medical University, Nagakute, Aichi, Japan.
Akio ShimizuDepartment of Palliative and Supportive Medicine, Graduate School of Medicine, Aichi Medical University, Nagakute, Aichi, Japan.
Koji AmanoDepartment of Palliative and Supportive Medicine, Graduate School of Medicine, Aichi Medical University, Nagakute, Aichi, Japan.
Naoharu MoriPalliative Care Center, Aichi Medical University, Nagakute, Aichi, Japan.
Aichi Medical University · JPAichi Medical University Hospital · JP

Funding

KAKENHI, Japan Society for the Promotion of Science 22K11839
6 · The paper itself

Abstract

backgroundRecently, the Asian Working Group for Cachexia (AWGC) published a consensus statement on diagnostic criteria for cachexia in Asians. We aimed to validate the criteria in adult patients in Japan with advanced cancer.

methodsWe conducted a single-institution retrospective cohort study between April 2021 and October 2022. The AWGC criteria include chronic comorbidities and either a weight loss of >2% over 3-6 months or a body mass index (BMI) of <21 kg/m

resultsOf the 449 consecutive patients, 85 of those who could not be evaluated because of end-of-life or refractory symptoms (n = 41) or missing data (n = 44) were excluded from the primary analysis. The prevalence of the AWGC-defined cachexia was 76% (n = 277), and the median survival time (MST) for all patients was 215 (95% confidence interval [CI] 145-270) days. The prevalence of the following criteria was significantly higher in patients with cachexia than in those without cachexia: a BMI of <21 kg/m

conclusionsWe demonstrated that AWGC-defined cachexia has a significant prognostic value in advanced cancer.

Indexed as

CachexiaLung NeoplasmsAdultAgedAnorexiaFemaleHumansMaleRetrospective StudiesWeight Losscancer cachexiadiagnostic criteriaprognosisThe Asian Working Group for Cachexia

Identifiers

PMID38115133
PMCPMC10834352
OpenAlexW4390012423

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.