Evidence map›Paper›PMID 38115118›Full record

ArticleVirology journal2023

Detection of parechovirus A in respiratory, gastrointestinal, and neurological clinical samples of pediatric patients from Panama (2014-2015).

Lizette Gutierrez, Viridiana Sáenz, Danilo Franco, Brechla Moreno, Ediner Fuentes-Campos, Zeuz Capitan-Barrios, Luis Felipe Rivera, Jean-Paul Carrera, Juan Castillo, Marlene Castillo and 4 more

Open access · goldAbstract read
In one paragraph

Article in Virology journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 2 countries.

Lizette Gutierrez *The University of Texas at El Paso (UTEP), El Paso, TX, 79968, US.
Viridiana Sáenz *The University of Texas at El Paso (UTEP), El Paso, TX, 79968, US.
Danilo FrancoDepartment of Research in Virology and Biotechnology, Gorgas Memorial Institute of Health Studies, Panama City, Panama.
Brechla MorenoDepartment of Research in Virology and Biotechnology, Gorgas Memorial Institute of Health Studies, Panama City, Panama.
Ediner Fuentes-CamposDepartment of Research in Virology and Biotechnology, Gorgas Memorial Institute of Health Studies, Panama City, Panama.
Zeuz Capitan-BarriosFacultad de Ciencias Naturales, Exactas y Tecnología, Departamento de Microbiología y Parasitología, Universidad de Panamá, Panamá, Panama.ORCID 0000-0002-2481-1057
Luis Felipe RiveraDepartment of Research in Virology and Biotechnology, Gorgas Memorial Institute of Health Studies, Panama City, Panama.
Jean-Paul CarreraDepartment of Research in Virology and Biotechnology, Gorgas Memorial Institute of Health Studies, Panama City, Panama.ORCID 0000-0002-1459-2858
Juan CastilloDepartment Research in Genomic and Proteomic, Gorgas Memorial Institute of Health Studies, Panama City, Panama.
Marlene CastilloDepartment of Research in Virology and Biotechnology, Gorgas Memorial Institute of Health Studies, Panama City, Panama.
Juan Miguel PascaleDepartment of Research in Virology and Biotechnology, Gorgas Memorial Institute of Health Studies, Panama City, Panama.
Sandra López-VergèsDepartment of Research in Virology and Biotechnology, Gorgas Memorial Institute of Health Studies, Panama City, Panama.ORCID 0000-0002-1106-8479
Néstor SosaDepartment of Research in Virology and Biotechnology, Gorgas Memorial Institute of Health Studies, Panama City, Panama.
Leyda ÁbregoDepartment of Research in Virology and Biotechnology, Gorgas Memorial Institute of Health Studies, Panama City, Panama. labrego@gorgas.gob.pa.ORCID 0000-0002-2708-4668
Instituto Conmemorativo Gorgas de Estudios de la Salud · PAUniversidad de Panamá · PA

Funding

U.S. Mexico Interdisciplinary Research Training ProgramT37MD001376 · NIMHD · UNIVERSITY OF TEXAS EL PASO · PI DUARTE-GARDEA, MARIA O. · 2005 to 2018
$3.2M
NIMHD NIH HHS 5T37MD001376-2012
6 · The paper itself

Abstract

Parechovirus A (PeV-A, Parechovirus, Picornaviridae) are human pathogens associated with mild to severe gastrointestinal and respiratory diseases in young children. While several studies have investigated the association of PeV-A with human disease, little is known about its epidemiology or detection in Latin America. Between the years 2014 and 2015, a total of 200 samples were collected from Panamanian pediatric patients aged < 16 years old exhibiting symptoms associated with respiratory (n = 64), gastrointestinal (n = 68), or neurological (n = 68) diseases. These samples were gathered from patients who had previously received negative diagnoses for the main respiratory viruses, rotavirus, and neurological viruses like herpes virus, enterovirus, and cytomegalovirus. The presence of PeV-A was analyzed by real time RT-PCR.Eight positive PeV-A infections (4.0%, 95% CI: 1.7 to 7.7) were detected: two in respiratory samples (3.0%, 95% CI: 0.3 to 10.8), five in gastrointestinal samples (7.3%, 95% CI: 2.4 to 16.3), and one in cerebrospinal fluid (1.5%, 95% CI: 1.4 to 7.9). The study provides evidence of PeV-A circulation in Panama and the data collectively, remarked on the importance of considering PeV-A in the Panamanian pediatric diagnostic landscape, especially when conventional testing for more common viruses yields negative results.

Indexed as

EnterovirusEnterovirus InfectionsParechovirusPicornaviridaePicornaviridae InfectionsAdolescentChildChild, PreschoolHumansInfantGastrointestinal infectionNeurological infectionPanamaPeVPeV-ARespiratory infection

Identifiers

PMID38115118
PMCPMC10731877
OpenAlexW4389937121

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.