Evidence map›Paper›PMID 38115069›Full record

ArticleScandinavian journal of trauma, resuscitation and emergency medicine2023

Prehospital blood gas analyses in acute patients treated by a ground-based physician-manned emergency unit: a cohort study.

Louise Houlberg Walther, Annmarie Touborg Lassen, Christian Backer Mogensen, Erika Frischknecht Christensen, Søren Mikkelsen

Open access · goldAbstract read
In one paragraph

Article in Scandinavian journal of trauma, resuscitation and emergency medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Louise Houlberg WaltherThe Prehospital Research Unit, Region of Southern Denmark, Odense University Hospital, Odense, Denmark. Louise.Houlberg.Walther@rsyd.dk.ORCID http://orcid.org/0000-0001-8555-363X
Annmarie Touborg LassenDepartment of Emergency Medicine, Odense University Hospital, Odense, Denmark.ORCID http://orcid.org/0000-0003-4942-6152
Christian Backer MogensenEmergency Medicine Research Unit, Hospital Soenderjylland, University Hospital of Southern Denmark, Aabenraa, Denmark.ORCID http://orcid.org/0000-0002-8254-089X
Erika Frischknecht ChristensenCentre for Prehospital and Emergency Research, Aalborg University Hospital and Institute of Clinical Medicine, Aalborg University, Aalborg, Denmark.ORCID http://orcid.org/0000-0003-3673-9694
Søren MikkelsenThe Prehospital Research Unit, Region of Southern Denmark, Odense University Hospital, Odense, Denmark.ORCID http://orcid.org/0000-0002-5187-7027
University of Southern Denmark · DKAalborg University Hospital · DKOdense University Hospital · DKSygehus Sønderjylland · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe prehospital patients treated by ambulances and mobile emergency care units (MECU) are potentially critically ill or injured. Knowing the risks of serious outcomes in these patients is important for guiding their treatment. Some settings allow for prehospital arterial blood gas analyses. This study aimed to assess the outcomes of prehospital patients in relation to their prehospitally measured lactate, pH, and CO

methodsThis register-based cohort study included patients with one or more prehospital blood gas analyses during their prehospital treatment by a physician-manned MECU, from January 2015 to December 2018. The blood samples were analyzed on an ABL90 Flex analyzer. Absolute values with percentages and odds ratios (OR) with 95% confidence intervals (CI) were calculated for the primary and secondary outcomes within prespecified subgroups.

resultsThe study included 745 patients, with an overall 7-day mortality rate of 20.0%. LACTATE LEVEL: The 7-day mortality rates were 11.5% in patients with normal lactate levels (< 2.0 mmol/L), 14.4% with intermediate lactate levels (2.0-3.9 mmol/L), and 33.0% with high lactate levels (≥ 4.0 mmol/L). This corresponded to an OR of 1.30 (95% CI: 0.75-2.24) in the intermediate lactate group (2.0-3.9 mmol/L) and an OR of 3.77 (95% CI: 2.44-5.85) in the high lactate group (≥ 4.0 mmol/L), compared to the reference group with normal lactate. PH LEVEL: The ORs of 7-day mortality rates were 4.82 (95% CI: 3.00-7.75) in patients with blood pH of < 7.35 and 1.33 (95% CI: 0.65-2.72) in patients with blood pH > 7.45, compared to the reference group with normal pH (7.35-7.45). CO2 LEVEL : The ORs of 7-day mortality rates were 2.54 (95% CI: 1.45-4.46) in patients with blood CO

conclusionsThis study found a strong correlation between increasing 7-day mortality rates and high blood lactate levels, low levels of pH, and abnormal CO

Indexed as

Emergency Medical ServicesPhysiciansBlood Gas AnalysisCarbon DioxideCohort StudiesEmergency Service, HospitalHumansLactic AcidCarbon DioxideLactic AcidBlood gasCarbon dioxidCO2Emergency medical servicesLactatepHPoint-of-carePrehospital

Identifiers

PMID38115069
PMCPMC10729417
OpenAlexW4389942540

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.