Evidence map›Paper›PMID 38114989›Full record

ArticleBMC medicine2023

Post-COVID-19 condition risk in patients with intellectual and developmental disabilities: a retrospective cohort study involving 36,308 patients.

Ting-Hui Liu, Po-Yu Huang, Jheng-Yan Wu, Min-Hsiang Chuang, Wan-Hsuan Hsu, Ya-Wen Tsai, Pei-Hsin Kao, Chih-Cheng Lai

Abstract read
In one paragraph

Article in BMC medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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  6. Addressing Inequalities in Long Covid Healthcare: A Mixed-Methods Study on Building Inclusive Services.Health expectations : an international journal of public participation in health care and health policy · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ting-Hui LiuDepartment of Psychiatry, Chi Mei Medical Center, No 901, Chunghwa Road, Yongkang District, Tainan City 710, Taiwan.
Po-Yu HuangDepartment of Internal Medicine, Chi Mei Medical Center, Tainan, Taiwan.
Jheng-Yan WuDepartment of Nutrition, Chi Mei Medical Center, Tainan, Taiwan.
Min-Hsiang ChuangDepartment of Internal Medicine, Chi Mei Medical Center, Tainan, Taiwan.
Wan-Hsuan HsuDepartment of Internal Medicine, Chi Mei Medical Center, Tainan, Taiwan.
Ya-Wen TsaiCenter for Integrative Medicine, Chi Mei Medical Center, Tainan, Taiwan.
Pei-Hsin KaoDepartment of Psychiatry, Chi Mei Medical Center, No 901, Chunghwa Road, Yongkang District, Tainan City 710, Taiwan. joek27@gmail.com.
Chih-Cheng LaiDivision of Hospital Medicine, Department of Internal Medicine, Chi Mei Medical Center, Tainan, Taiwan. dtmed141@gmail.com.ORCID 0000-0002-6334-2388

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo date, no studies have investigated the prevalence of post-COVID-19 conditions in patients with Intellectual and Developmental Disabilities (IDD). Addressing this research gap is crucial, as understanding post-COVID-19 conditions in IDD patients can improve care planning, and it is essential not to overlook this vulnerable population in COVID-19 studies. This study was aimed at investigating the prevalence of post-COVID-19 conditions in patients with IDD and compare their risk with that of the general population.

methodsUsing the TriNetX network, we identified patients with and without an IDD who had COVID-19. Subsequently, we compared the risk of developing any post-COVID-19 condition between these two groups, during the 90-180-day follow-up after SARS-CoV-2 infection.

resultsDuring the follow-up, patients with an IDD exhibited a significantly higher prevalence of post-COVID-19 conditions compared to the general population (hazard ratio [HR], 1.120; 95% confidence interval [CI]: 1.053-1.191). Specifically, COVID-19 survivors with IDD had a significantly increased risk of experiencing abnormal breathing (HR, 1.216; 95% CI: 1.077-1.373), abdominal symptoms (HR, 1.259; 95% CI: 1.128-1.406), fatigue (HR, 1.397; 95% CI: 1.216-1.606), anxiety/depression (HR, 1.157; 95% CI: 1.050-1.274), cognitive symptoms (HR, 1.828; 95% CI: 1.529-2.186), myalgia (HR, 1.325; 95% CI: 1.077-1.631), sleep disturbances (HR, 1.481; 95% CI: 1.148-1.910), and cough (HR, 1.315; 95% CI: 1.146-1.508) compared to the non-IDD group.

conclusionsPatients with IDD might be associated with a higher risk of post-COVID-19 conditions following SARS-CoV-2 infection compared to the general population.

Indexed as

COVID-19Intellectual DisabilityChildChronic DiseaseDevelopmental DisabilitiesHumansPost-Acute COVID-19 SyndromeRetrospective StudiesSARS-CoV-2COVID-19Intellectual and developmental disabilityPost-COVID-19 conditionSARS-CoV-2

Identifiers

PMID38114989
PMCPMC10731815

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.